Sökning: "FCAT"

Hittade 2 avhandlingar innehållade ordet FCAT.

  1. 1. Clinical and experimental studies on oxidized fragrance terpenes as contact allergens

    Författare :Johanna Bråred Christensson; Göteborgs universitet; []
    Nyckelord :autoxidation; contact allergy; limonene; linalool; colophonium; limonene-1-hydroperoxide; limonene-2-hydroperoxide; 15-hydroperoxyabietic acid; 15-HPA; terpenes; local lymph node assay; LLNA; Freunds complete adjuvant test; FCAT; patch testing; laser Doppler imaging; skin irritation; visual reading;

    Sammanfattning : The work presented in this thesis aims to improve the possibilities for diagnosing contact allergy to oxidized limonene and linalool and to, in patients, study contact allergy from structurally closely related hydroperoxides with regard to their specificity, potency and cross-reactivity. The fragrance terpenes limonene (from citrus oil) and linalool (from lavender oil) are widely used in household and industrial products. LÄS MER

  3. 2. Predictive testing for contact allergy : comparison of some guinea pig and mouse protocols including dose-response designs

    Författare :Helen Wahlkvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :contact allergens; contact allergy; cumulative contact enhancement test; dose-response; evaluation; Freund s complete adjuvant test; guinea pig maximization test; local lymph node assay; mouse ear swelling test; patch test; predictive testing; statistical analysis;

    Sammanfattning : Contact allergy (delayed hypersensitivity) may develop as a result of skin exposure to contact allergens (haptens) and can lead to allergic contact dermatitis. The purpose of this study was to evaluate some predictive animal test methods for contact allergens. LÄS MER