Sökning: "guinea pig maximization test"
Hittade 4 avhandlingar innehållade orden guinea pig maximization test.
1. Contact allergens in p-tert-butylphenol-formaldehyde resin
Sammanfattning : p-tert-Butylphenol-formaldehyde resin (PTBP-F-R) is used as a binder in many adhesive formulations and it consists of a complex mixture of substances, most of which are unknown. The resin has been reported to cause allergic contact dermatitis since the 1950s. LÄS MER
2. Experimental and Clinical Studies on Contact Allergy to Diphenylmethane-4,4′-diisocyanate and Related Substances
Sammanfattning : The exposure to isocyanates is more of an occupational problem than a consumer problem. The main route of exposure is assumed to be through inhalation. Isocyanates that have high vapor pressure, such as TDI, can be airborne at room temperature. Other isocyanates such as MDI are volatile only when heated. LÄS MER
3. Methylisothiazolinones. Diagnosis and prevention of allergic contact dermatitis
Sammanfattning : Preservatives are biologically active substances which are required in water-based products/systems to prevent growth of micro-organisms. Kathon® CG (K-CG), one of several preservatives based on 5-chloro-2-methyl-4-isothiazolinon-3-one (MCI) and 2-methyl-4-isothiazolin-3-one (MI) has been shown to be a common sensitizer in dermatitis patients. LÄS MER
4. Predictive testing for contact allergy : comparison of some guinea pig and mouse protocols including dose-response designs
Sammanfattning : Contact allergy (delayed hypersensitivity) may develop as a result of skin exposure to contact allergens (haptens) and can lead to allergic contact dermatitis. The purpose of this study was to evaluate some predictive animal test methods for contact allergens. LÄS MER