Sökning: "Dermatologi och venereologi"

Visar resultat 6 - 10 av 192 avhandlingar innehållade orden Dermatologi och venereologi.

  1. 6. Skin Barrier Function and mRNA Expression Profiles in Patients with Atopic Dermatitis, Ichthyosis Vulgaris, and X-linked Recessive Ichthyosis : Aetiopathogenic Differences and the Impact of Moisturizing Treatment

    Författare :Torborg Sturesdotter Hoppe; Berit Berne; Hans Törmä; Anders Vahlquist; Charlotta Enerbäck; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atopic dermatitis; ichthyosis vulgaris; X-linked recessive ichthyosis; skin barrier function; moisturizers; transepidermal water loss; gene expression; Dermatologi och venereologi; Dermatology and Venerology;

    Sammanfattning : Atopic dermatitis (AD), ichthyosis vulgaris (IV), and X-linked recessive ichthyosis (XLRI) are characterized by dry skin and impaired skin barrier. AD and IV are related to loss-of-function mutations in FLG (encoding filaggrin), whereas XLRI is caused by deletions or inactivating mutations in the steroid sulphatase gene (STS). LÄS MER

  3. 7. Congenital Recessive Ichthyosis : Studies of Gene Expressions Related to Keratinocyte Differentiation and Skin Barrier Repair

    Författare :Hanqian Zhang; Hans Törmä; Anders Vahlquist; Marie Virtanen; Mikael Ivarsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; genodermatoses; oligoarray; trancriptomics; transglutaminase-1; cornified envelope; peroxisome proliferator-activated receptor δ; all-trans retinoic acids.; Dermatologi och venereologi; Dermatology and Venerology;

    Sammanfattning : Autosomal recessive congenital ichthyosis (ARCI) is a rare monogenetic disorder characterized by a defective skin barrier, hyperkeratosis, and dry, scaly skin. It affects keratinocyte differentiation and is caused by mutations in any of at least 12 genes believed to control the formation of ω-O-acylceramide and the corneocyte lipid envelope (CLE): ABCA12, ALOXE3, ALOX12B, CERS3, CYP4F22, ELOVL4, LIPN, NIPAL4, PNPLA1, SDR9C7, SLC27A4, and TGM1. LÄS MER

  4. 8. Non-coding RNAs and Extracellular Vesicles in Cutaneous Squamous Cell Carcinoma

    Författare :Chen Li; Andor Pivarcsi; Gareth Inman; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cutaneous squamous cell carcinoma; microRNA; long non-coding RNA; extracellular vesicle;

    Sammanfattning : Cutaneous squamous cell carcinoma (cSCC) ranks among the most widespread malignancies with metastatic potential. Investigating the molecular mechanism of tumorigenesis will enhance our understanding of cSCC. Aberrant expression of non-coding RNAs has been extensively reported in human cancers. LÄS MER

  5. 9. Clinical and experimental studies in nickel allergy

    Författare :Monica Hindsén; Dermatologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nickel absorption; Nickel; allergic contact dermatitis; patch test reactivity; flare-up reactions; oral nickel provocation; previous contact dermatitis; hand eczema; atopy; Dermatology; venereology; Dermatologi; venereologi;

    Sammanfattning : Kliniska och experimentella studier av nickelallergi Nickelallergi är vanligt, särskilt hos kvinnor. Nickelallergi leder ofta till periodiskt eller kroniskt eksem, främst på händerna. Dessa eksem kan vara svårläkta och leda till långa sjukskrivningsperioder. LÄS MER

  7. 10. Characterisation and treatment of patients with port wine stains with special reference to the emotional impact

    Författare :Agneta Troilius; Dermatologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; capillary malformation; PWS; pulsed dye laser; laser doppler imager; ultrasound; psychosocial impact; depth; reflectance spectrophotometry; Dermatologi; venereologi; venereology; Dermatology;

    Sammanfattning : This thesis covers 12 years of experience in treating patients with congenital capillary malformations, so called port wine stains (PWS). The wide variation in treatment response to laser therapy has developed a profound need for the development of objective devises to measure treatment outcome, so that the maximum effectiveness of therapy can be achieved without unnecessary treatments. LÄS MER