Sökning: "1H NMR"
Visar resultat 16 - 20 av 124 avhandlingar innehållade orden 1H NMR.
16. Characterising Weak Interactions in Solution. : An NMR Spectroscopic Approach
Sammanfattning : Detecting and characterising weak interactions in dilute solutions is challenging. This thesis focusses on the development of a new NMR spectroscopic strategy to do so, whilst also investigates a newly proposed type of weak interaction in solution with currently available NMR techniques. LÄS MER
17. Profiling Plasma Metabolite Alterations in Diet-Induced Obesity and Diabetes Using NMR Metabolomics
Sammanfattning : Diets rich in saturated fat and sedentary lifestyles markedly contribute to obesity and metabolic syndrome-related diseases, including type 2 diabetes mellitus (T2D). Metabolite profiling plays a pivotal role in understanding these metabolic diseases. LÄS MER
18. Mechanistic Studies of Organocopper Chemistry by NMR Spectroscopy: Conjugate Additions to Alkynes and Alkenes
Sammanfattning : This thesis focuses on the mechanisms of organocopper reactions, in particular the reactions with activated alkynes (ynoates and ynones). These reactions are of interest in the formation of new highly functionalized double bonds with control of the stereochemistry. LÄS MER
19. Solid-State NMR Characterization of Lipid Membranes
Sammanfattning : This thesis deals with the study of lipid bilayer systems by solid-state nuclear magnetic resonance. Two-dimensional 1H-13C separated local field experiments under magic-angle spinning were employed to investigate structural and dynamical modifications of cell membranes, resulting from the addition of compounds with some biological relevance. LÄS MER
20. The Application of isotropic bicelles as model membranes
Sammanfattning : Isotropic bicelles are disc-shaped aggregates of lipids and detergents, and are suitable model systems for high-resolution NMR studies of membrane-interacting peptides. In this thesis the structures for the two peptides motilin and transportan were determined by homonuclear 1H methods in the presence of bicelles, and the structure of the bovine prion protein peptide (bPrPp) was solved in the presence of DHPC micelles. LÄS MER