Sökning: "diet-induced obesity"
Visar resultat 1 - 5 av 50 avhandlingar innehållade orden diet-induced obesity.
1. Profiling Plasma Metabolite Alterations in Diet-Induced Obesity and Diabetes Using NMR Metabolomics
Sammanfattning : Diets rich in saturated fat and sedentary lifestyles markedly contribute to obesity and metabolic syndrome-related diseases, including type 2 diabetes mellitus (T2D). Metabolite profiling plays a pivotal role in understanding these metabolic diseases. LÄS MER
2. Modulators of UCP1-dependent thermogenesis : Glucocorticoids, diet and novel research models
Sammanfattning : The activation and recruitment of brown adipose tissue (BAT) thermogenesis has been put forward as a promising strategy to reduce the disease burden of obesity and obesity-related diseases. Heat production by BAT can be attributed to the tissue-specific mitochondrial uncoupling protein 1 (UCP1). LÄS MER
3. Energy flow and metabolic efficiency attributed to brown adipose tissue
Sammanfattning : The large capacity of brown adipose tissue (BAT) to expend energy as heat makes it an interesting potential player in weight regulation and other metabolic conditions. This is of particular interest as it has been recognized that adult humans possess BAT. LÄS MER
4. Dietary, Pharmacological and Environmental Effects on Brown Adipose Tissue
Sammanfattning : Obesity is a common health issue; over 12 % of the adult world population have obesity. Obesity has many co-morbidities including cardo-vascular diseases and diabetes. Obesity is the result of chronic positive energy balance, eating too much and expending too little. LÄS MER
5. Genes implicated in the development of obesity and obesity-related disease
Sammanfattning : Obesity is a major health problem because of its dramatic increase in prevalence and the association of obesity with type 2 diabetes, coronary heart disease, hypertension and stroke. Although mutations in certain genes have been shown to cause obesity, the molecular mechanisms underlying obesity and obesity-related disease are still largely unknown. LÄS MER