Sökning: "tissue-resident"

Visar resultat 36 - 40 av 40 avhandlingar innehållade ordet tissue-resident.

  1. 36. Human cytotoxic lymphocyte differentiation in health and disease

    Författare :Heinrich Schlums; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cytotoxic lymphocytes, comprising natural killer (NK) cells and CD8+ cytotoxic T cells, eradicate infected or malignant cells by release of lytic granules and alarm the immune system through production of pro-inflammatory cytokines and chemokines. NK cells and CD8+ T cells belong to different arms of the immune system, employing complementary strategies for target cell recognition. LÄS MER

  3. 37. Breathe (in the air) : pulmonary immunology in multiple sclerosis

    Författare :Michael Hagemann-Jensen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple Sclerosis (MS) is a demyelinating disease of the central nervous system, with etiology still unknown. MS is thought to arise from a complex interplay between genetic and environmental factors. LÄS MER

  4. 38. Scarring and regeneration in the central nervous system

    Författare :Jannis Kalkitsas; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In response to injury, tissues employ conserved reparative mechanisms to heal the damage and recover their function. The reparative success varies according to the organism, the tissue or organ, and the age of the specimen. The reparative response occurs through two separate but overlapping processes: wound healing and regeneration. LÄS MER

  5. 39. The ontogeny and function of intestinal dendritic cells

    Författare :Emma Persson; Slemhinnans immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mesenteric lymph nodes; Intestine; Dendritic cells; Gut-homing; Th17 cells; Oral tolerance; Immunity;

    Sammanfattning : The intestinal mucosa presents a huge surface area to the external environment and the intestinal immune system is continually exposed to a wide array of foreign antigens derived from resident intestinal microbiota as well as dietary constituents, including food proteins. In order to maintain intestinal homeostasis, the intestinal immune system relies on the ability to generate tolerogenic responses to innocuous antigen while maintaining the ability to develop effective immune responses to intesinal pathogens. LÄS MER

  7. 40. Deciphering the complexity of psoriasis : non-coding RNAs and cellular interactions

    Författare :Longlong Luo; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Psoriasis is a prevalent immune-mediated skin disorder marked by chronically relapsing inflammation and epidermal hyperproliferation. As researchers delve deeper into the molecular intricacies of psoriasis, emerging evidence hints at the roles of non-coding RNAs (ncRNAs). LÄS MER