Sökning: "quinine"

Visar resultat 16 - 20 av 22 avhandlingar innehållade ordet quinine.

  1. 16. Natural Products from Cameroonian Medicinal Plants

    Författare :Apollinaire Tsopmo; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Växtbiokemi; Plant biochemistry; antiplasmodial.; antitrypanosomal; diarylheptanoids; terpenoids; flavonoids; aframodial; Aframomum; Reneilmia cincinnata; Dorstenia; Euphorbia; Lepidobotrys staudtii; Pentadiplandra brazzeanea; Vernonia guineensis; Natural products; Myrica arborea;

    Sammanfattning : Natural product chemistry is a main research area in Cameroon, as well as for the division of Bioorganic Chemistry at Lund Institute of Technology. A review of the results obtained recently with Cameroonian medicinal plants shows that a large number of compounds, many with complex structures, have been isolated and characterised, and the work presented in this thesis is part of this effort. LÄS MER

  3. 17. Studies on 4b-hydroxycholesterol, a marker of CYP3A activity, and its association with 25-hydroxyvitamin D

    Författare :Hanna Nylén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cholesterol is a vital compound that can undergo cytochrome P450 (CYP) mediated conversion into steroid hormones, bile acids and oxysterols. CYP enzymes are present in all human tissues and mediate the metabolism of several endogenous and exogenous compounds such as steroids and drugs. LÄS MER

  4. 18. Induction of human cytochrome P450 enzymes : predictive in vitro models and rifampicin induction in vivo

    Författare :Kajsa P Kanebratt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The cytochrome P450 (P450) enzymes comprise the most important enzyme system with regard to phase I metabolism of drugs. Induction of P450s can result in decreased plasma concentrations of the drug itself or a coadminstered drug, followed by lack of effect. LÄS MER

  5. 19. Clinical studies of CYP3A4 and P-glycoprotein

    Författare :Erik Sparve; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In the field of pharmacokinetics, cytochrome P450 enzymes have been extensively studied. The CYP450 enzyme with the most drug substrates is CYP3A4, but despite its significance, administration of a specific substrate to subjects is required to determine its activity, by measuring the metabolic ratio. LÄS MER

  7. 20. Airway hyperresponsiveness and viral recognizing toll-like receptors

    Författare :Magnus Starkhammar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Common colds caused by viruses are, in healthy individuals, usually self-limited and with relatively mild symptoms. In asthmatic individuals, respiratory viruses can burst the defense immune system and trigger asthma exacerbations, including causing airway hyperresponsiveness (AHR). LÄS MER