Sökning: "Erik Sparve"

Hittade 1 avhandling innehållade orden Erik Sparve.

1. 1. Clinical studies of CYP3A4 and P-glycoprotein

   Författare :Erik Sparve; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : In the field of pharmacokinetics, cytochrome P450 enzymes have been extensively studied. The CYP450 enzyme with the most drug substrates is CYP3A4, but despite its significance, administration of a specific substrate to subjects is required to determine its activity, by measuring the metabolic ratio. LÄS MER