Sökning: "depressive mood"

Visar resultat 21 - 25 av 92 avhandlingar innehållade orden depressive mood.

  1. 21. Gene-environment factors in depressive disorders with a focus on circadian genes

    Författare :Louise Sjöholm; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Depressive disorders have a multifactorial etiology, where both environmental and genetic risk factors contribute. Depression is characterized by a depressed mood and accompanied by e.g. loss of interest and pleasure, disturbed sleep and appetite and difficulties in concentrating. LÄS MER

  2. 22. On the efficacy and prescription of serotonin reuptake inhibitors

    Författare :Alexander Lisinski; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antidepressants; antidepressive agents; major depressive disorder; selective serotonin reuptake inhibitor; serotonin and noradrenaline reuptake inhibitor; tricyclic antidepressant;

    Sammanfattning : This thesis addresses several controversial issues regarding commonly used antidepressants, including selective serotonin reuptake inhibitors (SSRIs), serotonin and noradrenaline reuptake inhibitors (SNRIs), and tricyclic antidepressants (TCAs). To this end, patient-level data from 28 placebo-controlled trials on SSRIs and 13 corresponding trials on the SNRI duloxetine, were requested and obtained. LÄS MER

  3. 23. On the Effects of Serotonin Reuptake Inhibitors in Major Depression

    Författare :Fredrik Hieronymus; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antidepressants; antidepressive agents; depression; major depressive disorder; selective serotonin reuptake inhibitor; SNRI; SSRI;

    Sammanfattning : This thesis focuses on the antidepressant effects of selective serotonin reuptake inhibitors (SSRIs) and how these are reflected by the Hamilton Depression Rating Scale (HDRS). To this end, we have assembled a large data set of placebo-controlled SSRI trials in major depression, and used this for a series of post-hoc patient-level analyses. LÄS MER

  4. 24. Studies on neuronal signaling in the hippocampus related to development, pathogenesis and treatment of mood disorders

    Författare :Nermin Sourial-Bassillious; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Hippocampus;

    Sammanfattning : The hippocampus is a central organ in the brain which is interconnected with different cortical regions and plays an important role in memory and learning processes. The anatomical position of the hippocampus together with the special sensitivity of its neurons renders it vulnerable to brain injury. LÄS MER

  5. 25. Depression and partner violence before and after childbirth

    Författare :Christine Rubertsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Depression; depressive mood; post partum depression; partner violence; risk factors; EPDS; stressful life events; domestic violence; partner violence;

    Sammanfattning : This thesis comprises studies of prevalence and indicators of depressive mood during pregnancy, two months and one year post partum as well as on studies of prevalence, and indicators of being hit by the partner in the first post partum year and disclosure of such violence. A national cohort of 4600 Swedish-speaking women were recruited to the KUB project (Kvinnors Upplevelse av Barnafödande) and consists of about 70 percent of women enrolled in early pregnancy to antenatal care during three predestined weeks. LÄS MER