Sökning: "tricyclic antidepressant"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden tricyclic antidepressant.

  1. 1. On the efficacy and prescription of serotonin reuptake inhibitors

    Författare :Alexander Lisinski; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antidepressants; antidepressive agents; major depressive disorder; selective serotonin reuptake inhibitor; serotonin and noradrenaline reuptake inhibitor; tricyclic antidepressant;

    Sammanfattning : This thesis addresses several controversial issues regarding commonly used antidepressants, including selective serotonin reuptake inhibitors (SSRIs), serotonin and noradrenaline reuptake inhibitors (SNRIs), and tricyclic antidepressants (TCAs). To this end, patient-level data from 28 placebo-controlled trials on SSRIs and 13 corresponding trials on the SNRI duloxetine, were requested and obtained. LÄS MER

  3. 2. Characterization of secretory mechanisms in lacrimal and salivary glands

    Författare :Martin Dankis; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dry mouth; dry eyes; antidepressant; muscarinic; purinergic; salivary secretion; tear secretion; lacrimal gland; in vivo; primary culture; co-culture; acinar; myoepithelial;

    Sammanfattning : Dry mouth and dry eyes are multifactorial morbidities that can lead to a severely reduced quality of life. Approximately 20% of the population suffers from ocular or oral dryness. LÄS MER

  4. 3. Acute lung failure induced by tricyclic antidepressants : an experimental evaluation

    Författare :Karin Svens; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :ARDS; tricyclic antidepressants; isolated lungs; rat; endothelin; endothelial cells; tight junctions;

    Sammanfattning : The tricyclic antidepressant drugs (TCA) have, over the years, been reported to be able to cause adult respiratory distress syndrome (ARDS)/acute lung injury in connection with overdose, and are currently among the most common cause of self-poisoning. Approximately 10% of all TCA overdose patients develop ARDS, and the treatment of these patients, irrespective of the event causing ARDS, is mainly supportive. LÄS MER

  5. 4. The treatment of depression in clinical practice : a public health perspective

    Författare :Svante Henriksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Depression; treatment of depression; antidepressant medication; public health;

    Sammanfattning : Depression is a major public health problem with a reported point prevalence of 5%. Depressive illness causes great suffering and disability. Effective treatment with antidepressant drugs has been available for more than 40 years. LÄS MER

  7. 5. Serotonin in emotional memory processes : neuropharmacological studies with emphasis on depression

    Författare :Therese M Eriksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cognitive dysfunctions are common in neuropsychiatric disorders including Major Depressive Disorder, but are difficult to normalize by antidepressant therapies and contribute to reduced functional improvement. Cognitive impairments include alterations of emotional memory processes that are early targeted by antidepressant therapies, including Selective Serotonin Reuptake Inhibitors (SSRIs). LÄS MER