Sökning: "cancer vaccines"

Visar resultat 16 - 20 av 69 avhandlingar innehållade orden cancer vaccines.

1. 16. Hsp70 in immunotherapy : a potential vector in cancer and viral vaccines

   Författare :Anne-Marie T Ciupitu; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :heat shock protein 70; vaccination; tumour antigens; in vivo protection; T cell activation; adjuvant; LCMV;

   Sammanfattning : New efficient vaccines against cancers and infectious diseases are in demand. In 1993 heat shock protein 70 (hsp70) purified from tumour was shown to elicit tumour protection in mice. It was also shown that the protection was not mediated by the hsp70 itself, but by tumour-specific peptides bound to the molecule. LÄS MER

3. 17. Strengthening the pillars of cancer immunotherapy

   Författare :Maarten Alexander Ligtenberg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The treatment of disease in cancer patients by harnessing the potent mechanisms that exist within the immune system is not a novel approach, and has been first attempted more than a century ago. During the major part of this century cancer immunotherapy has been relegated to the periphery of standard care for patients. LÄS MER

4. 18. Risk factors for cervical cancer development

   Författare :Anthony S Gunnell; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Cervical cancer remains one of the leading causes of cancer mortality globally, predominantly in less developed countries. It is widely accepted that certain oncogenic types of HPV (Human papillomavirus) are necessary causes of cervical cancer development and a number of co-factors (including smoking) have also been implicated. LÄS MER

5. 19. Exosomes : immunomodulators in cancer and therapy

   Författare :Stefanie Hiltbrunner; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Exosomes are nano-sized membrane vesicles derived from the late endosomal compartment. They are capable of transferring proteins, lipids and RNA between cells. B cell and dendritic cell (DC)-derived exosomes express major histocompatibility complex (MHC) class I and II, as well as costimulatory molecules (CD80/86) and can initiate T cell responses. LÄS MER

7. 20. Clinical implications of HPV in oropharyngeal cancer

   Författare :Per Attner; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Tonsillar cancer incidence has been increasing in Sweden and many other western countries in the last decades despite that other head and neck cancers are decreasing. It is now established that Human Papillomavirus (HPV) can be accredited part of that increase. LÄS MER