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1. Integrin α2 and Akt in early hematopoiesis
Sammanfattning : Hematopoiesis is a tightly regulated process in which hematopoietic stem cells reside at the apex of the hierarchy, and produce all kinds of mature blood cells by differentiation to replenish the cell loss in homeostasis and acute injury. In past few decades, much effort has been made to purify hematopoietic stem cells (HSCs) and lineagecommitted progenitor cells both in mouse and human, enabling further characterization of these cell populations not only in normal hematopoiesis, but also in various hematological malignancies. LÄS MER
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