Sökning: "Proportional Hazards"

Visar resultat 26 - 30 av 77 avhandlingar innehållade orden Proportional Hazards.

  1. 26. Studies as a basis for a possible introduction of newborn screening for cystic fibrosis in Sweden

    Författare :Isabelle de Monestrol; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Cystic fibrosis (CF) is the most common life-shortening autosomal recessive disease in Caucasians. It is a multi-organ disease that results from mutations in the gene that encodes the CF transmembrane conductance regulator (CFTR) protein, which regulates ion transport at epithelial surfaces. LÄS MER

  3. 27. Reliability analysis and maintenance scheduling considering operating conditions

    Författare :Dhananjay Kumar; Luleå tekniska universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Mining and Rock Engineering; Gruv- och Berganläggningsteknik;

    Sammanfattning : In reliability analysis failure times are often considered as the only factor that can explain the reliability characteristics of a system. This may be insufficient. Operating conditions and other factors (e.g. LÄS MER

  4. 28. Deliberate self-harm : characteristics, clinical correlates and interventions

    Författare :Hanna Sahlin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Deliberate self-harm (DSH) and nonsuicidal self-injury (NSSI) are serious global health problems prevalent among both community and clinical samples. Several studies have suggested that aggression towards others may be a clinically relevant correlate in self-harming individuals, but the association is still unclear. LÄS MER

  5. 29. Development and application of competing risks and multi-state models in cancer epidemiology

    Författare :Nikolaos Skourlis; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Competing risks and multi-state models allow us to study complex disease settings and answer composite research questions and should be used more widely in epidemiology. This thesis aims to explore the competing risks and multi-state models areas using flexible parametric survival models (FPSMs), studying several aspects, such as the choice of timescale, choice of multi-state structure, sharing information across transitions by imposing restrictions in the estimation of the parameters, as well as communicating the results of such models to a wider audience and evaluating the use of recurrent multi-state structures in the area of recurrent events when a terminal event is present. LÄS MER

  7. 30. A cohort study of sex differences and prognostic biomarkers in colorectal cancer

    Författare :Sakarias Wangefjord; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer; prognosis; treatment prediction; biomarkers; sex differences; cyclin D1; microsatellite instability; beta-catenin; KRAS mutation; BRAF mutation; EGFR expression; EGFR gene copy number alterations;

    Sammanfattning : Colorectal cancer (CRC) is one of the most common forms of cancer worldwide, with an annual incidence of more than 1 million cases. Despite advancements in the management of CRC, mortality remains high. LÄS MER