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1. 1. Clinical studies of asthma phenotypes focusing on the role of the leukotrienes

   Författare :Per Gyllfors; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :>asthma; aspirin intolerance; leukotrienes; leukotriene D4 responsiveness; methacholine responsiveness; exhaled nitric oxide;

   Sammanfattning : Inflammation in the airways in connection to asthma is a complex phenomenon and the mechanisms underlying the associated clinical symptoms involve the interaction of many different kinds of cells and mediators, giving rise to different phenotypes. The aim of the present thesis was to investigate the molecular and cellular mechanisms that results in two of these phenotypes, i. LÄS MER