Sökning: "Meiqiongzi Zhang"

Hittade 1 avhandling innehållade orden Meiqiongzi Zhang.

1. 1. Making sense from nonsense and missense : pharmacological rescue of mutant tumor suppressor p53

   Författare :Meiqiongzi Zhang; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : A large fraction of human tumors carry inactivating mutations in the TP53 tumor suppressor gene. Approximately 75% of these mutations are missense mutations and around 10% are nonsense mutations. TP53 inactivation allows evasion of cell death and rapid tumor progression. LÄS MER