Sökning: "Exendin-4"

Visar resultat 16 - 17 av 17 avhandlingar innehållade ordet Exendin-4.

  1. 16. IL-6 and GLP-1 in body fat regulating parts of the CNS in healthy mice

    Författare :Fredrik Anesten; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IL-6; IL-6Rα; GLP-1; obesity; hypothalamus; brainstem; tanycytes; immunohistochemistry;

    Sammanfattning : It has previously been shown that mice lacking interleukin-6 (IL-6) develop mature onset obesity. The weight-suppressing effects of IL-6 have been assumed to be exerted at a central level, as supported by the fact that ICV- injections, but not peripheral injections of IL-6, increases energy expenditure and decreases body fat in rodents. LÄS MER

  3. 17. Development of therapeutics for the treatment of diabetic brain complications

    Författare :Shiva Mansouri; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Type-2 diabetes (T2D) is characterized by hyperglycemia and hyperlipidemia, resulting in impaired insulin production and insulin resistance in peripheral tissues. Several studies have demonstrated an association between diabetes and central nervous system complications such as stroke and Alzheimer’s disease. LÄS MER