Sökning: "Ana Cristina Rego"

Hittade 1 avhandling innehållade orden Ana Cristina Rego.

1. 1. Molecular mechanism(s) underlying neurodegeneration in SCA7 disease : Role of NOX enzymes and oxidative stress

   Författare :Abiodun Ajayi; Anna-Lena Ström; Ana Cristina Rego; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; neurodegeneration; oxidative stress; NOX; metabolism; p53; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

   Sammanfattning : Spinocerebellar ataxia type 7 (SCA7) is an autosomal dominant neurodegenerative disorder caused by a CAG trinucleotide expansion in the SCA7 gene resulting in progressive ataxia and retinal dystrophy. SCA7 belongs to a group of neurodegenerative disorders called polyglutamine (polyQ) diseases, that share the common feature of glutamine tract expansions within otherwise unrelated proteins. LÄS MER