Sökning: "vinyl azide"

Hittade 3 avhandlingar innehållade orden vinyl azide.

  1. 1. Lewis acid Mediated Aza-Diels-Alder Reactions and Asymmetric Alkylations of 2H-azirines

    Författare :Erik Risberg; KTH; []
    Nyckelord :Enantioselective; diastereoselective; vinyl azide; 2H-azirines; aziridines; Lewis acid; chiral ligand; chiral auxiliary organolithiums Diels-Alder reaction alkyl radicals triethylborane.;

    Sammanfattning : This thesis describes the use of 2H-azirines, three-membered unsaturatednitrogen-containing heterocycles, as reactive intermediates ina number of Lewis acid promoted alkylations and Diels-Alderreactions providing synthetically useful aziridines. In order to carry out this investigation a new generalprocedure for the ring closure of vinyl azides, forming theresultant 3-substituted-2H-azirines, was developed applying low boiling solventsin closed reaction vessels at elevated temperatures. LÄS MER

  3. 2. Development of Lewis acid mediated stereoselective synthesis of nitrogen containing heterocycles

    Författare :Åsa Sjöholm Timén; KTH; []
    Nyckelord :organic chemistry;

    Sammanfattning : This thesis deals with the development of syntheticmethodologies for the preparation of enantio- anddiastereomerically enriched nitrogen-containingheterocycles.Asymmetric Lewis acid mediated Diels-Alder reactions with2H-azirines as dienophiles have been studied. LÄS MER

  4. 3. Design and Synthesis of 11C-Labelled Compound Libraries for the Molecular Imaging of EGFr, VEGFr-2, AT1 and AT2 Receptors : Transition-Metal Mediated Carbonylations Using [11C]Carbon Monoxide

    Författare :Ola Åberg; Bengt Långström; Nicholas Long; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; [11C]carbon monoxide; isotopic labelling; PET; acrylamide; EGFR; VEGFR-2; 11C; Organic chemistry; Organisk kemi; Organic Chemistry; Organisk kemi; Organic Pharmaceutical Chemistry; Organisk farmaceutisk kemi;

    Sammanfattning : This work deals with radiochemistry and new approaches to develop novel PET tracers labelled with the radionuclide 11C.Two methods for the synthesis of 11C-labelled acrylamides have been explored. LÄS MER