Sökning: "tubular cells"
Visar resultat 1 - 5 av 76 avhandlingar innehållade orden tubular cells.
1. Cellular and molecular mechanisms of kidney injury and regeneration
Sammanfattning : The prevalence of kidney disease is constantly increasing with about 600 million people afflicted globally. Kidney disease may result in end stage renal disease, a condition that requires renal replacement therapy in the form of kidney transplantation or dialysis. LÄS MER
2. Role of tubular scattered cells of the kidney in disease and regeneration
Sammanfattning : With well over 700 000 deaths every year worldwide, kidney disease constitutes an immense health problem for patients and society. The total global number of people with kidney disease regardless of severity amounts to a staggering 600 000 000. LÄS MER
3. Mesenchymal stem cells for repair of the peripheral and central nervous system
Sammanfattning : Bone marrow-derived mesenchymal stem cells (MSC) have been shown to provide neuroprotection after transplantation into the injured nervous system. The present thesis investigates whether adult human and rat MSC differentiated along a Schwann cell lineage could increase their expression of neurotrophic factors and promote regeneration after transplantation into the injured peripheral nerve and spinal cord. LÄS MER
4. Roles of the Shb and Cbl Proteins in Signal Transduction and Blood Vessel Formation
Sammanfattning : Formation of blood vessels occurs through two processes: vasculogenesis and angiogenesis, which are regulated by various growth factors such as vascular endothelial growth factor, fibroblast growth factor and platelet-derived growth factor. The present study was carried out in order to investigate the roles of the Shb and Cbl proteins in growth factor-mediated signal transduction and blood vessel formation. LÄS MER
5. ADAMTS13 phenotype in health and disease with special reference to thrombotic thrombocytopenic purpura
Sammanfattning : Von Willebrand factor (VWF) is synthesized and secreted by endothelial cells into the plasma as a series of multimers. VWF induces the formation of platelet plugs at sites of vascular injury and high shear stress. Biological activity is dependent on multimeric size, which is regulated in plasma by the VWF-cleaving protease ADAMTS13. LÄS MER
