Sökning: "tissue-type plasminogen activator"

Visar resultat 1 - 5 av 30 avhandlingar innehållade orden tissue-type plasminogen activator.

  1. 1. Tissue-type plasminogen activator : molecular interactions with plasminogen activator inhibitor-1 and endothelial cell-surface proteins

    Författare :Maria Ljung; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : .... LÄS MER

  2. 2. Plasminogen : a novel inflammatory regulator that promotes wound healing

    Författare :Yue Shen; Tor Ny; Gunilla Høyer-Hansen; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Plasminogen; inflammation; wound healing; diabetic wounds; tympanic membrane perforations; medicinsk biokemi; Medical Biochemistry;

    Sammanfattning : The plasminogen activator (PA) system has been shown to be intimately involved in wound healing. However, the role of this system in the initiation and resolution of inflammation during healing process remained to be determined. LÄS MER

  3. 3. Genetic variation at the human tissue-type plasminogen activator locus

    Författare :Per Ladenvall; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tissue-type plasminogen activator; single-nucleotide polymorphism; vascular release; myocardial infarction; enhancer; Sp1.;

    Sammanfattning : Tissue-type plasminogen activator (tPA) is the key initiator of intravascular fibrinolysis. Family studies suggest that tPA release is regulated by hereditary factors. LÄS MER

  4. 4. Endogenous tissue-type plasminogen activator andendothelial function in vivo. A clinical perspective

    Författare :Thorarinn Gudnason; Göteborgs universitet; []
    Nyckelord :tissue-type plasminogen activator; endothelial function; age; vasodilation; chronic heart failure; coronary artery disease; local regulation; perfused-forearm model;

    Sammanfattning : Endogenous fibrinolysis is initiated by the glycoprotein tissue-type plasminogen activator (tPA), which is released from the vascular endothelium. Plasminogen activator inhibitor type 1 (PAI-1) is the main inhibitor of tPA. LÄS MER

  5. 5. Regional fluxes of tissue plasminogen activator in porcine endotoxemia

    Författare :Annette Nyberg; Göteborgs universitet; []
    Nyckelord :pig; endotoxin; tissue type plasminogen activator; plasminogen activator inhibitor; tumor necrosis factor ?;

    Sammanfattning : Formation of fibrin clots in the microcirculation during severe sepsis contributes to organ failure, frequently involving the lungs and the splanchnic organs. Tissue type plasminogen activator, tPA, is the key activator of intravascular fibrinolysis with plasminogen activator inhibitor type-1, PAI-1, as its main inhibitor. LÄS MER