Sökning: "small airways."

Visar resultat 11 - 15 av 49 avhandlingar innehållade orden small airways..

  1. 11. Extracellular Matrix Alterations in Patients with Different Phenotypes of Asthma

    Författare :Maria Weitoft; Lungbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Asthma; Extraceullar matrix; Proteoglycan; Collagen; Hyaluronan; Fibrocyte; Mast cell; Nitric oxide;

    Sammanfattning : AbstractAsthma is a chronic disease that affects approximately 300 million people worldwide, and the prevalence is increasing. It has become clear that asthma is a highly heterogeneous disease, with overlapping symptoms but with diverse immunopathology and clinical phenotypes. LÄS MER

  3. 12. The Role of FCGBP in Mucus - Structure, Processing and Function

    Författare :Erik Ehrencrona; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mucus; FCGBP; IgG; IBD; COPD; Mucins; Disulphide; GDPH;

    Sammanfattning : In this thesis, a bottom-up approach was used to study the IgG Fc-binding protein (FCGBP), which next to the MUC2 mucin is the second main component of secreted mucus in small intestine and colon. FCGBP is also found in airways during inflammatory conditions with static mucus. LÄS MER

  4. 13. Particle transport in human lung : effects of particle size and shape

    Författare :Sofie Högberg; Luleå tekniska universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Strömningslära; Fluid Mechanics;

    Sammanfattning : Recent studies have shown that nanoparticles may be more toxic than larger particles of the same material, but the health risks associated with widespread use largely depend on the extent of exposure. When dealing with potentially toxic particles, precautionary measures have to be taken in order to minimize contact. LÄS MER

  5. 14. Prostaglandin E2 as mediator and modulator of airway smooth muscle responses

    Författare :Jesper Säfholm; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Prostaglandin E2 (PGE2) is a lipid mediator produced by virtually every cell of the human body. Because common non-steroidal anti-inflammatory drugs (NSAIDs) inhibit its biosynthesis, PGE2 is usually considered to be a ‘pro-inflammatory’ mediator. The role of PGE2 in the lung and airways has however always been unclear. LÄS MER

  7. 15. Airway smooth muscle as a target in asthma : new insights into bronchorelaxation and hyperreactivity

    Författare :Martijn Manson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Patients with asthma suffer from reversible airway obstruction accompanied by airway hyperresponsiveness (AHR). Airway smooth muscle (ASM) is central to bronchoconstriction and AHR and is therefore the target of existing and potential new therapies for asthma. LÄS MER