Sökning: "sLex"

Visar resultat 6 - 10 av 13 avhandlingar innehållade ordet sLex.

  1. 6. Helicobacter pylori : molecular insights into regulation of adhesion properties

    Författare :Pär Gideonsson; Anna Arnqvist; Thomas Borén; Hilde De Reuse; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Helicobacter pylori; medicinsk biokemi; Medical Biochemistry;

    Sammanfattning : Helicobacter pylori infects the human stomach and triggers an inflammatory response that damages the gastric tissue. This host-pathogen interplay has dire consequences as up to 20 % of infected individuals develop peptic ulcer disease or gastric cancer. LÄS MER

  3. 7. Human α2,3-sialyltransferases. Structure and Function of Alternatively Spliced Transcripts

    Författare :Ammi Grahn; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; a2; 3-sialyltransferase; isotranscript; isoenzyme; alternative splicing; capillary electrophoresis;

    Sammanfattning : The recruitment of human peripheral blood leukocytes to sites of infection and inflammation requires the surface expression of Sialyl Lewis x glycoconjugates (SLex) on white blood cells and their interaction with E- and P-selectins on activated endothelial cells. Human ST3Gal III, ST3Gal IV and ST3Gal VI genes code for a2,3?sialyltransferases potentially involved in the biosynthesis of the SLex epitope. LÄS MER

  4. 8. Adaptation of Helicobacter pylori Adherence Properties in Promotion of Host Tropism and Inflammatory Disease

    Författare :Marina Aspholm; Rino Rappuoli; Umeå universitet; []
    Nyckelord :H. pylori; BabA; SabA; adhesin; blood group antigens; sialylated; phase variation; hemagglutination; selectin; adaptation; odontologi; Odontology;

    Sammanfattning : Being among the most prevalent of persistent infectious agents in humans worldwide, Helicobacter pylori induces chronic inflammation (gastritis), which may progress to peptic ulceration and stomach cancer. The ability to adhere to the gastric mucosa is considered to be both a colonization and virulence property of H. pylori. For adherence, H. LÄS MER

  5. 9. Helicobacter pylori : bacterial adhesion and host response

    Författare :Farzad Olfat; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Communicable diseases; Infektionssjukdomar; Infectious diseases; Infektionssjukdomar;

    Sammanfattning : The gastric pathogen Helicobacter pylori infects more than half of the population worldwide. H. pylori manage to establish persistent infection, which would be life-long if not treated. In order to establish such an infection, this pathogen has to deal with the host immune system. LÄS MER

  7. 10. Glycan dependent Helicobacter spp. and Streptococcus oralis binding to mucins in the gastric and oral mucosal niches

    Författare :Gurdeep Chahal; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Helicobacter pylori; Streptococcus; diversity; glycosylation;

    Sammanfattning : Helicobacter pylori infects the stomach of half of the world’s population, while Helicobacter suis colonizes pigs and is the most common non-H. pylori Helicobacter species that also infects human stomach. Infection with Helicobacter spp. is associated with chronic gastritis, peptic ulcer disease, and gastric cancer. LÄS MER