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Hittade 2 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Sensory mechanisms in the human upper airway - Role of TRP ion channels

   Författare :Lisa Alenmyr; Avdelningen för klinisk kemi och farmakologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TRPV1; TRPV4; TRPA1; allergic rhinitis; itch; rhinorrhea; MUC5B; MUC5AC; epithelial;

   Sammanfattning : The nasal mucosa is richly innervated with sensory nerves having the ability to detect changes in the environment and mediate symptoms such as secretion and itch. Some TRP ion channels such as TRPV1 and TRPA1 are abundantly expressed in sensory nerves and respond to a wide variety of stimuli, including irritants, inflammatory mediators and temperatures. LÄS MER

3. 2. Endogenous and exogenous glucocorticoid effects in a model of allergic airway inflammation

   Författare :Susanna Kumlien Georén; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Airway; allergy; asthma; eosinophil; glucocorticoids; hypothalamus-pituitary-adrenal HPA axis; inflammation; nerve growth factor NGF ; neuroimmunology; psychoneuroimmunology; restraint; stress;

   Sammanfattning : Allergic asthma and rhinitis are inflammatory diseases of the airways. Allergic asthma is characterized by eosinophilic inflammation, reversible bronchoconstriction and airway hyperresponsiveness, whereas patients with rhinitis suffer from nasal inflammation, leading to rhinorrhea and nasal congestion. LÄS MER