Sökning: "reaktiva syreradikaler"

Visar resultat 1 - 5 av 8 avhandlingar innehållade orden reaktiva syreradikaler.

  1. 1. Surface reactions on metallic nanoparticles : Ligand adsorption, metal release, and reactive oxygen species generation

    Författare :Amanda Kessler; Inger Odnevall; Tommy Nylander; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; metallic nanoparticles; ROS; reactive oxygen species; metal release; ligand adsorption; corrosion; Fenton like Haber Weiss reactions; metalliska nanopartiklar; ROS; reaktiva syreradikaler; metallfrisättning; adsorption; korrosion; Fenton lika Haber Weiss reaktioner; Kemi; Chemistry;

    Sammanfattning : Humans are exposed daily to metallic nanoparticles (Me NPs) from multiple sources which can have both natural and anthropogenic origins. Such exposures take place via different routes including inhalation and skin contact and may result in adverse health effects. LÄS MER

  3. 2. Candida albicans adaption to host microenvironments drives immune evasion

    Författare :José Pedro Lopes; Constantin F. Urban; Alistair Brown; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; fungi; candida albicans; neutrophils; mast cells; immune evasion; mycoses; infectious diseases; immunologi; Immunology; Infectious Diseases; infektionssjukdomar; Molecular Immunology; molekylär immunologi;

    Sammanfattning : Immunosuppressed patients are frequently afflicted with severe mycoses caused by opportunistic fungal pathogens. Besides being a commensal colonizing predominantly skin and mucosal surfaces, Candida albicans is the most common human fungal pathogen. LÄS MER

  4. 3. Gene-environment interactions for arsenic metabolism and metal-related oxidatively generated DNA damage

    Författare :Karin Engström; Avdelningen för arbets- och miljömedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AS3MT; methylation; polymorphism; 8-oxodG;

    Sammanfattning : Over 100 million people around the world are exposed to high concentrations of arsenic (As) in drinking water, associated with a number of adverse health effects such as skin, lung and bladder cancer, vascular diseases and diabetes. In humans, As is metabolized via alternating reduction and methylation reactions, from inorganic As (iAs) into monomethylated (MMA) and dimethylated As (DMA). LÄS MER

  5. 4. Radical aspects on arthritis : the role of neutrophil generation of nitric oxide and superoxide in inflammatory conditions

    Författare :Jan Cedergren; Thomas Skogh; Tommy Sundqvist; Tony Forslund; Ingrid Lundberg; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neutrophils; reactive oxygen species; arthritis; NOS; NO; arginase; integrins; Internal medicine; Invärtesmedicin;

    Sammanfattning : The polymorphonuclear neutrophil granulocytes (neutrophils) are gaining renewed interest regarding their involvement in chronic inflammatory disorders, including rheumatoid arthritis (RA). Besides phagocytic and destructive capabilities, neutrophils have regulatory roles, e.g. by influencing responses from dendritic cells and lymphocytes. LÄS MER

  7. 5. The impact of glucotoxicity on pancreatic β-cell function

    Författare :Sarheed Jabar Muhammed; Islet cell physiology; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cAMP PKA system; iNOS; Type 2 diabetes; GSIS; PDE; GK rat; ZDF fa fa rat; GPR40; VDAC1; VDAC2; GSK-3β; ChREBP; TXNIP; resveratrol.;

    Sammanfattning : Type 2 diabetes mellitus is connected with elevated plasma glucose levels which negatively influence β-cells and cause impaired glucose-stimulated insulin secretion (GSIS). The aim of present thesis was to investigate the impact of long-term hyperglycemia on the pancreatic islet β-cell function. LÄS MER