Avancerad sökning

Visar resultat 1 - 5 av 105 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Novel inhibitors of Chlamydia trachomatis virulence

    Författare :Carlos Nunez-Otero; Åsa Gylfe; Sven Bergström; Fredrik Almqvist; Jörgen Johansson; Patrik Bavoil; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chlamydia trachomatis; 2-pyridone; small molecules; KSK213; Structure-Activity Relationships SAR ; antibiotic resistance; target identification; transcription; RNA; progeny; infectivity;

    Sammanfattning : Chlamydia trachomatis is an obligate intracellular bacterium that infects over 100 million people globally every year. Chlamydia infections can be persistent, cause infertility and blindness, adding an economical burden in the healthcare systems. LÄS MER

  3. 2. The ecological significance of cleistogamy

    Författare :Henrik Berg; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Ecology; bet-hedging; chasmogamous; enviromnental variation; fitness; outcrossing; progeny; selling; Ekologi; Terrestrial; freshwater and marine ecology; Terrestisk; limnisk och marin ekologi; ekologisk botanik; Ecological Botany;

    Sammanfattning : Various aspects of cleistogamy, a reproductive system combining selfing in closed (cleistogamous) flowers and potential outcrossing in open (chasmogamous) flowers, were investigated in four perennial species. The main purpose was to shed some light on the adaptive value of having a dual reproductive strategy, and to test some hypotheses on the maintenance of xenogamy. LÄS MER

  4. 3. Death mechanisms compromising hippocampal neurogenesis after status epilepticus

    Författare :Christine Ekdahl Clementson; Lund Neurologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi; minocycline; lipopolysaccharide; microglia activation; status epilepticus; epilepsy; cysteinyl aspartate-specific proteases; apoptosis; neurogenesis; progenitor cell progeny;

    Sammanfattning : Status epilepticus (SE) leads to neurodegeneration as well as neurogenesis in the adult rat hippocampus. This thesis demonstrates that even if the neurogenic response initially is very pronounced, with a several-fold increase in cell proliferation, the survival of the newly formed neurons is compromised by a death mechanism involving mitochondria-related caspases. LÄS MER

  5. 4. Progenitor cells in the postnatal central nervous system, characterization and genetic manipulation

    Författare :Nina Rogelius; CNS Genterapi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; subventricular zone; Islet1; Neurogenin2; respecification; in vivo.; transcription factors; neurogenesis; Progenitor cells; stem cells;

    Sammanfattning : New neurons are only generated in two places of the postnatal brain; the subventricular zone (SVZ) and hippocampus. The SVZ-derived cells specifically migrate to the olfactory bulb where they give rise to new interneurons. LÄS MER

  7. 5. Experimentell bestämning av klimatanpassning hos tall (Pinus silvestris L. och Pinus contorta Dougl.)

    Författare :Mats Hagner; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : This paper summarizes the content of three articles published in Studia Forestalia Suecica 80,81,82, 1970.A study of the annual grouuth rhythm on 2-, 3- and 20-year-old Pinus silvestris and 2-year-old Pinus contorta showed that the following methods can be used for experimental assessment of the climatic adaptation of populations and single trees: shoot- and needle elongation, bark colour onterminal, lignification of annual ring and water content of needles. LÄS MER