Sökning: "positron emission tomography PET"

Visar resultat 21 - 25 av 227 avhandlingar innehållade orden positron emission tomography PET.

1. 21. PET applications in schizophrenia : Functional and pharmacological dopamine studies

   Författare :Ola Gefvert; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Schizophrenia; PET; dopamine synthesis rate; dopamine D2 receptor occupancy; atypical antipsychotics; quetiapine; risperidone microsphere depot; Neurovetenskap; Neurology; Neurologi; Psychiatry; psykiatri;

   Sammanfattning : Schizophrenia is a group of disorders with a worldwide lifetime prevalence of 0.85%. Thefunctional outcome of the disorder seem stable from the first systematic outcome studies to thepresent day, and vary only with changes in diagnostic criteria. LÄS MER

3. 22. Positron emission tomography in serotonergic drug development

   Författare :Bengt Andrée; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :PET; 5-HT1A receptors; 5-HT2A receptors; D2 dopamine receptors; antidepressive drugs; antipsychotic drugs; pindolol; NAD-299; S 16924; ORG 5222; M100907; WAY; DWAY;

   Sammanfattning : The serotonin neurotransmission system has a central role in drug treatment of depression and anxiety and is also discussed in relation to treatment of schizophrenia. The benefits of presently available drugs are however limited by partial of poor response and side effects. LÄS MER

4. 23. Geometric distortions in MRI based radiotherapy and PET/MRI

   Författare :Josef Lundman; Tufve Nyholm; Anne Larsson; Jörgen Olofsson; Marco Riboldi; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Magnetic resonance imaging; MRI; PET MR; PET MRI; medical imaging; radiotherapy; geometrical distortions; MR-only; MRI-only; radiofysik; radiation physics;

   Sammanfattning : Magnetic resonance imaging (MRI) offers high soft-tissue contrast compared to computed tomography (CT). This contrast is helpful in many cases, not least for delineating tumours for radiotherapy treatment, and has led to increasing use in radiotherapy treatment planning (RTP). LÄS MER

5. 24. Translational PET imaging of inflammation

   Författare :Emmi Puuvuori; Olof Eriksson; Tove Grönroos; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PET imaging; Nuclear Medicine; Inflammation; Translational Medicine;

   Sammanfattning : Inflammation is our body’s sophisticated defense mechanism against invading pathogens, traumas, and tumors. Repeatable and non-invasive monitoring of inflammation process would open opportunities to improve our knowledge of several diseases and enable assessment of personalized treatments. LÄS MER

7. 25. Visualising neurodegeneration in the living brain : Preclinical evaluation of PET radioligands

   Författare :Mengfei Xiong; Stina Syvänen; Sahar Roshanbin; Joakim Bergström; Per Borghammer; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Positron emission tomography PET ; Alzheimer s disease; Parkinson s disease; SV2A; neurodegeneration; immunotherapy; transgenic mice; Medicinsk vetenskap; Medical Science; Analytical Chemistry; Analytisk kemi; Pharmacology; Farmakologi; Molekylär medicin; Molecular Medicine;

   Sammanfattning : With an ageing population, the number of people suffering from Alzheimer’s disease (AD) and Parkinson’s disease (PD) escalates yearly. Pathological hallmarks of AD and PD include aggregated proteins and synaptic dysfunction. LÄS MER