Sökning: "mitochondrial ribosome"
Visar resultat 1 - 5 av 18 avhandlingar innehållade orden mitochondrial ribosome.
1. The interactome of the yeast mitochondrial ribosome : Organization of mitochondrial post-transcriptional regulation, membrane protein insertion and quality control
Sammanfattning : The proteins found in mitochondria originate from two different genetic systems. Most mitochondrial proteins are synthesized in the cytosol and post-translationally imported into the organelle. However, a small subset of mitochondrial proteins is encoded in an organelle-resident genome. LÄS MER
2. Mitochondrial translation and its impact on protein homeostasis and aging
Sammanfattning : Besides their famous role as powerhouse of the cell, mitochondria are also involved in many signaling processes and metabolism. Therefore, it is unsurprising that mitochondria are no isolated organelles but are in constant crosstalk with other parts of the cell. LÄS MER
3. On the Origin and Evolution of the Mitochondrial Ribosome
Sammanfattning : The ribosome is among the most ancient, intricate and well studied macromolecular complexes in biology. Predating the earliest divergence of life, its core molecular structure has remained mostly unchanged for more than three billion years. LÄS MER
4. Organization and regulation of mitochondrial gene expression
Sammanfattning : Mitochondria possess their own genome, remnant of the ancestral eubacterial endosymbiont DNA. This mitochondrial genome encodes mostly few key subunits of the respiratory chain. In order to synthesize these few proteins, mitochondria contain a complete gene expression machinery. LÄS MER
5. Computational Studies of Protein Synthesis on the Ribosome and Ligand Binding to Riboswitches
Sammanfattning : The ribosome is a macromolecular machine that produces proteins in all kingdoms of life. The proteins, in turn, control the biochemical processes within the cell. It is thus of extreme importance that the machine that makes the proteins works with high precision. LÄS MER
