Sökning: "liver fibrosis"

Visar resultat 1 - 5 av 64 avhandlingar innehållade orden liver fibrosis.

1. 1. Ultrasound based shear wave elastography of the liver : a non-invasive method for evaluation of liver disease

   Författare :Marie Byenfeldt; Anders Elvin; Per Fransson; Odd Helge Gilja; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anthropometric measurement; diagnostic imaging; elasticity imaging technique; blood supply; BMI; body position; fatty liver; liver disease; hepatic steatosis; liver fibrosis; liver stiffness; obesity; postural change; pressure; probe; sex characteristic; shear wave elastography; skin-to-liver capsule distance; transducer and ultrasonography; Radiography; radiografi;

   Sammanfattning : Background: Detecting liver disease at an early stage is important, given that early intervention decreases the risk of developing cirrhosis and subsequently hepatocellular cancer (HCC). The non-invasive ultrasound-based shear wave elastography (SWE) has been used clinically for a decade to assess liver stiffness. LÄS MER

3. 2. Cellular and molecular mechanisms in immune mediated hepatic fibrosis. A study of the inflammatory syndrome and fibrosis development of the NIF mouse liver

   Författare :Julia Nilsson; Autoimmunitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fibrosis; liver; mouse model; NKT cells; type 2 inflammation; inflammasome;

   Sammanfattning : Fibrosis is the result of dysregulated inflammation and tissue repair, and is characterized by the excessive accumulation of extra cellular matrix (ECM) proteins. It causes detrimental effects to the afflicted tissue and can subsequently lead to organ failure. LÄS MER

4. 3. Hepatitis C virus infection. Viral genotypes and factors promoting liver fibrosis

   Författare :Johan Westin; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hepatitis C virus; genotypes; epidemiology; liver fibrosis; histology; scoring; prognosis; alcohol; liver steatosis;

   Sammanfattning : Hepatitis C virus (HCV) is associated with chronic infection in a majority of infected individuals. Chronic hepatitis C may result in liver cirrhosis or hepatocellular cancer and is therefore considered a major health problem worldwide. LÄS MER

5. 4. Liver-related complications and metabolic comorbidities during long-term follow-up of patients with Non-Alcoholic Fatty Liver Disease

   Författare :Kristina Önnerhag; Gastroenterologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chronic kidney disease CKD ; Epidemiology; Fibrosis; Hepatocellular cancer; Insulin resistance; Liver cirrhosis; Metabolic syndrome; NAFLD; NASH; Non-alcoholic fatty liver disease; non-alcoholic steatohepatitis;

   Sammanfattning : Background: Non-alcoholic fatty liver disease (NAFLD) is highly associated with the metabolic syndrome, and due to increasing prevalence of for example obesity it is now the most common liver disease in the world. A minority progress to advanced fibrosis/cirrhosis, which is associated with increased mortality, but it is not entirely clear which patients who have an increased risk of fibrosis. LÄS MER

7. 5. Role of Fatty Acid Composition in Non-Alcoholic Fatty Liver Disease: a Dietary Perspective : Results from Interventional and Observational Studies

   Författare :Michael Fridén; Ulf Risérus; Fredrik Rosqvist; Helen Lindqvist; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fatty acids; Diet; Biomarkers; NAFLD; Liver fat; Fibrosis; Cirrhosis; HCC; Nutrition; Nutrition;

   Sammanfattning : The overall aim of this doctoral thesis was to investigate the role of circulating, liver and dietary fatty acids in non-alcoholic fatty liver disease (NAFLD). For circulating and liver fatty acids, special emphasis was given to fatty acids reflecting diet. LÄS MER