Sökning: "mouse model"

Visar resultat 1 - 5 av 1145 avhandlingar innehållade orden mouse model.

  1. 1. The Biological Importance of the Amino Acid Transporter SLC38A10 : Characterization of a Knockout Mouse

    Författare :Frida A. Lindberg; Robert Fredriksson; Erika Roman; Karin Nordenankar; Vootele Vöikar; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Solute carrier; SLC; SNAT10; SLC38A10; phenotyping; behavior; amino acids; knockout mouse model; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : The biggest group of transporters, the solute carriers (SLCs), has more than 400 members, and about 30% of these are still orphan. In order to decipher their biological function and possible role in disease, there is a need for characterization of these. LÄS MER

  3. 2. Uterus transplantation. An experimental study in the mouse

    Författare :Randa Racho El-Akouri; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; implantation; ischemia; mouse; pregnancy; rejection; transplantation; uterus;

    Sammanfattning : Uterus transplantation is a possible future treatment for uterine factor infertility, which can be either congenital (uterus agenesis/hypoplasia) or acquired (hysterectomy or intrauterine adhesions). The present study represents experiments where an animal model for uterine transplantation was developed and characterized. LÄS MER

  4. 3. Stochastic modelling and analysis of early mouse development

    Författare :Sofia Tapani; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; correlation; CUSUM; mouse; non-stationarity; pronucleus; stochastic differential equation; time series; wavelet decomposition; yeast; CUSUM;

    Sammanfattning : The aim of this thesis is to model and describe dynamical events for biological cells using statistical and mathematical tools. The thesis includes five papers that all relate to stochastic modelling of cells. LÄS MER

  5. 4. Strategies for postoperative adhesion control

    Författare :Kristina Falk; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adhesion formation; adhesion prevention; experimental model; mouse; human; fibrinolysis; bioadhesion; cellulose; hydrophobic modification; t-PA; PAI-1; proCPU; TAFI;

    Sammanfattning : Introduction: Abdominal surgery almost inevitably leads to adhesion formation, which often results in substantial morbidity. The formation of postsurgical adhesions seems to be determined by the balance of fibrin deposition and degradation in an early phase of peritoneal tissue repair. LÄS MER

  7. 5. Molecular and Cellular Control of Palate Development in the Mouse

    Författare :Forugh Vazirisani; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cleft palate; fate mapping; Sonic hedgehog; apoptosis; extracellular matrix; mouse;

    Sammanfattning : The formation of a definitive secondary palate in mammals is a multistep process that comprises growth, elevation, contact and fusion of the two palatal shelves. Disruption at any step generates cleft palate, a major congenital birth defect. Therefore, it is important to understand the mechanisms governing normal palate development. LÄS MER