Sökning: "ligand distribution"
Visar resultat 1 - 5 av 91 avhandlingar innehållade orden ligand distribution.
1. Direct observation of biomolecule adsorption and spatial distribution of functional groups in chromatographic adsorbent particles
Sammanfattning : Confocal microscopy has been used as a tool for studying adsorption of biomolecules to individual chromatographic adsorbent particles. By coupling a fluorescent dye to protein molecules, their penetration into single adsorbent particles could be observed visually at different times during batch uptake. LÄS MER
2. Application of Raman and Fluorescence Spectroscopy to Single Chromatographic Beads
Sammanfattning : Chromatography is a powerful technique, essential in chemical analyses and preparative separation in industry and research. Many different kinds of chromatographic material are needed, due to the large variety of applications. Detailed methods of characterisation are needed to design new chromatographic materials and understand their properties. LÄS MER
3. Characterization of [18F]flutemetamol binding properties : A β-amyloid PET imaging ligand
Sammanfattning : The criteria for diagnosing Alzheimer’s disease (AD) have recently been revised to include the use of biomarkers for the in vivo presence of β-amyloid, one of the neuropathological hallmarks of AD. Examples of such biomarkers are positron emission tomography (PET) β-amyloid specific ligands, including [18F]flutemetamol. LÄS MER
4. Galanin : Studies by Modification of the Ligand and the Receptor
Sammanfattning : This thesis is devoted to the deeper understanding of the molecular details of the interaction between the neuropeptide galanin and its target protein, the G-protein coupled 7TM galanin receptor. The enzymatic control of galanin degradation and second messenger systems triggered by galanin receptor activation are also studied. LÄS MER
5. On the Character of Active Sites in Copper Exchanged Zeolites during NH3-SCR
Sammanfattning : Nitrogen oxides (NOx) are formed during combustion in diesel engines and one current approach to reduce NOx to N2 is selective catalytic reduction with NH3 as reducing agent (NH3-SCR). To acquire both high activity and selectivity, the active site is often atomically dispersed metal atom, so-called single-site catalysts. LÄS MER