Sökning: "left-handed helix"

Hittade 4 avhandlingar innehållade orden left-handed helix.

  1. 1. Applications of Structural Bioinformatics for the Structural Genomics Era

    Författare :Marian Novotny; Gerard Kleywegt; Geoff Barton; Uppsala universitet; []
    Nyckelord :Bioinformatics; structural bioinformatics; fold comparison; left-handed helix; docking; solvent-accessible surface area; register shift; X-ray crystallography; Bioinformatik;

    Sammanfattning : Structural bioinformatics deals with the analysis, classification and prediction of three-dimensional structures of biomacromolecules. It is becoming increasingly important as the number of structures is growing rapidly. LÄS MER

  3. 2. Environmental influence on alpha-helical peptides

    Författare :Ana Caballero Herrera; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MD alpha helix; C-peptide; membrane proteins; hydrogen bonds; packing; dynamics;

    Sammanfattning : Most proteins at physiological conditions fold into a native functional three-dimensional conformation. The stability of the Native state is a balance between different interactions within the protein and with the solvent. LÄS MER

  4. 3. Structural Studies of Flexible Biomolecules and a DNA-binding Protein

    Författare :Tariq Massad; Pål Stenmark; Cheryl Arrowsmith; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Maximum entropy; motilin; DNA-binding proteins; Karplus equation; disaccaride; direct repeats; Structural biology; Strukturbiologi; Biophysics; biofysik;

    Sammanfattning : The knowledge of the three-dimensional structures of proteins and polypeptides is essential to understand their functions. The work shown in this thesis has two objectives. LÄS MER

  5. 4. Structural and functional studies of microsomal glutathione transferase 1

    Författare :Peter J Holm; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Glutathione transferase; membrane protein; three-dimensional structure; elecron crystallography; hydrophobic binding stoichiometry; H D exchange mass spectrometry;

    Sammanfattning : The microsomal glutathione transferase 1 (MGST1) is present in high amounts in the endoplasmic reticulum (ER) as an integral homo-trimeric membrane protein with a molecular weight of 51.9 kDa. LÄS MER