Sökning: "interneurons"

Visar resultat 16 - 20 av 113 avhandlingar innehållade ordet interneurons.

  1. 16. Computer Modelling of Neuronal Interactions in the Striatum

    Författare :Johannes Hjorth; Jeanette Hellgren Kotaleski; Kevin Gurney; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; striatum; fast spiking interneurons; medium spiny projection neurons; gap junctions; interoperability; MUSIC; Computer science; Datavetenskap;

    Sammanfattning : Large parts of the cortex and the thalamus project into the striatum,which serves as the input stage of the basal ganglia. Information isintegrated in the striatal neural network and then passed on, via themedium spiny (MS) projection neurons, to the output stages of thebasal ganglia. LÄS MER

  2. 17. The Role of miRNA in Neurogenesis and Cell Specification

    Författare :Malin Åkerblom; Molekylär neurogenetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; miRNA; microRNA; miR-124; miR-9; miR-125; adult neurogenesis; neural stem cells; cell specification; microglia; lentiviral vectors; olfactory bulb; olfactory bulb interneurons;

    Sammanfattning : Only a few decades ago, it was generally believed that gene expression was controlled in a unidirectional way, i.e. DNA was transcribed into RNA, which simply acted as a messenger molecule used to produce the protein that executed cellular functions. LÄS MER

  3. 18. Untangling Cortico-Striatal Circuitry and its Role in Health and Disease - A computational investigation

    Författare :Jovana Belic; Jeanette Hellgren Kotaleski; Arvind Kumar; Abigail Morrison; Arthur Leblois; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cortico-striatal circuits; levodopa-induced dyskinesia; Parkinson’s disease; effective connectivity; cross-frequency coupling; corticostriatal network; network oscillations; GABAergic transmission. basal ganglia; striatum; cortex; fast spiking interneurons; medium spiny neurons; neuronal avalanches;

    Sammanfattning : The basal ganglia (BG) play a critical role in a variety of regular motor and cognitive functions. Many brain diseases, such as Parkinson’s diseases, Huntington’s disease and dyskinesia, are directly related to malfunctions of the BG nuclei. LÄS MER

  4. 19. Organization of the spinal locomotor network in zebrafish : pattern of recruitment and origin of excitatory drive

    Författare :Emma Eklöf Ljunggren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Locomotion is of vital importance for animals to survive in a complex environment. Locomotor movements are generated by neuronal networks that reside in the spinal cord and are composed of motoneurons and interneurons. LÄS MER

  5. 20. Interneuron diversity and function in the zebrafish locomotor circuits

    Författare :Eva Rebecka Björnfors; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : One of the most essential features of an animal’s behavior is the ability to navigate and interact with its environment. The generation of the locomotor rhythm is carried out by networks of neurons in the spinal cord, so called central pattern generators (CPGs). LÄS MER