Sökning: "cross-frequency coupling"

Hittade 2 avhandlingar innehållade orden cross-frequency coupling.

  1. 1. Untangling Cortico-Striatal Circuitry and its Role in Health and Disease - A computational investigation

    Författare :Jovana Belic; Jeanette Hellgren Kotaleski; Arvind Kumar; Abigail Morrison; Arthur Leblois; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cortico-striatal circuits; levodopa-induced dyskinesia; Parkinson’s disease; effective connectivity; cross-frequency coupling; corticostriatal network; network oscillations; GABAergic transmission. basal ganglia; striatum; cortex; fast spiking interneurons; medium spiny neurons; neuronal avalanches;

    Sammanfattning : The basal ganglia (BG) play a critical role in a variety of regular motor and cognitive functions. Many brain diseases, such as Parkinson’s diseases, Huntington’s disease and dyskinesia, are directly related to malfunctions of the BG nuclei. LÄS MER

  2. 2. On the role of parvalbumin interneurons in neuronal network activity in the prefrontal cortex

    Författare :Nicolas Gustavo Guyon; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The prefrontal cortex (PFC) is an area important for executive functions, the initiation and temporal organization of goal-directed behavior, as well as social behaviors. Inhibitory interneurons expressing parvalbumin (PV) have a vital role in modulating PFC circuit plasticity and output, as inhibition by PV interneurons on excitatory pyramidal neurons regulates the excitability of the network. LÄS MER