Sökning: "interneurons"

Visar resultat 11 - 15 av 113 avhandlingar innehållade ordet interneurons.

  1. 11. Development and preclinical assessment of novel therapies for Epilepsy. Exploring the potential of human-derived cell lines and glial cell line-derived neurotrophic factor for network inhibition

    Författare :Eliska Waloschkova; Epilepsicentrum; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epilepsy; epileptogenesis; inhibition; cell therapy; GABAergic interneurons; mesenchymal stem cells; GDNF;

    Sammanfattning : Epilepsy is one of the leading neurological disorders affecting not only patients who suffer from seizures but also people around them and society in general. The striking one third of patients not responding to pharmacological treatments implies the necessity of developing alternative options for controlling seizures in these individuals. LÄS MER

  3. 12. On the Determination, Differentiation and maturation of Developing retinal Interneurons

    Författare :Per-Henrik D Edqvist; Uppsala universitet; []
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  4. 13. Inhibition in cognition : neurophysiology and connectivity of gabaergic interneurons in the prefrontal cortex

    Författare :Josina Anna van Lunteren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The prefrontal cortex (PFC) is a cortical region involved in higher-order cognitive functions, it is widely connected to the rest of the neocortex and is involved in tasks that require temporal integration of information. The local PFC circuit contains excitatory pyramidal neurons and inhibitory interneurons, and the interplay between these is essential for computations in the PFC. LÄS MER

  5. 14. Differences in glutamatergic transmission onto interneurons and pyramidal cells in the rat hippocampus

    Författare :Ilse Riebe; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AMPA; development; glutamate transmission; hippocampus; interneuron; NMDA; synapse;

    Sammanfattning : In the human brain there are about 100 billion excitatory glutamatergic neurons and 10 billion inhibitory GABAergic neurons. During development, these neurons are synaptically wired together into neural networks, functionally prepared to perform the full register of brain functions, and to learn from experiences. LÄS MER

  7. 15. On the role of parvalbumin interneurons in neuronal network activity in the prefrontal cortex

    Författare :Nicolas Gustavo Guyon; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The prefrontal cortex (PFC) is an area important for executive functions, the initiation and temporal organization of goal-directed behavior, as well as social behaviors. Inhibitory interneurons expressing parvalbumin (PV) have a vital role in modulating PFC circuit plasticity and output, as inhibition by PV interneurons on excitatory pyramidal neurons regulates the excitability of the network. LÄS MER