Sökning: "striatum"

Visar resultat 1 - 5 av 256 avhandlingar innehållade ordet striatum.

  1. 1. Information processing in the Striatum : a computational study

    Författare :Johannes Hjorth; Jeanette Hellgren Kotaleski; Anders Lansner; Kim Blackwell; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; striatum; fast spiking interneuron; gap junctions; synchronisation; up-state detection; CaMKII; mathematical modelling; Neuroscience; Neurovetenskap;

    Sammanfattning : The basal ganglia form an important structure centrally placed in the brain. They receive input from motor, associative and limbic areas, and produce output mainly to the thalamus and the brain stem. The basal ganglia have been implied in cognitive and motor functions. LÄS MER

  3. 2. Computer Modelling of Neuronal Interactions in the Striatum

    Författare :Johannes Hjorth; Jeanette Hellgren Kotaleski; Kevin Gurney; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; striatum; fast spiking interneurons; medium spiny projection neurons; gap junctions; interoperability; MUSIC; Computer science; Datavetenskap;

    Sammanfattning : Large parts of the cortex and the thalamus project into the striatum,which serves as the input stage of the basal ganglia. Information isintegrated in the striatal neural network and then passed on, via themedium spiny (MS) projection neurons, to the output stages of thebasal ganglia. LÄS MER

  4. 3. Dopamine and the affective-cognitive gradient in the human striatum studied with multimodal brain imaging

    Författare :Filip Grill; Anna Rieckmann; Lars Nyberg; Alison Adcock; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dopamine; striatum; incentive; motor; associative; reinforcement learning; reward prediction error; positron emission tomography; functional magnetic resonance imaging; PET MR; cognitive modelling;

    Sammanfattning : Both dopamine and the dopamine rich brain area, striatum, have been linked to behaviors related to incentives, motor action, and associative processing. Most of the cortex sends projections to the striatum, these connections have been described as a gradient organization representing a repertoire of functional behaviors. LÄS MER

  5. 4. On striatum in silico

    Författare :Johanna Frost Nylén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The basal ganglia are a collection of subcortical nuclei involved in movement and action selection. The striatum is the main input nucleus with extensive projections from the cortex and thalamus, and dopaminergic projections from SNc and VTA. LÄS MER

  7. 5. Neuroprotection and neurogenesis after experimental stroke

    Författare :Andreas Arvidsson; Lund Neurologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; stereology; rat; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi; BrdU; immunohistochemistry; in situ hybridization; subventricular zone; striatum; dentate gyrus; neuronal replacement; neuronal survival; Focal cerebral ischemia; glial cell line-derived neurotrophic factor;

    Sammanfattning : In this thesis, two potential endogenous mechanisms for neuronal survival and repair have been investigated in a rat model of stroke, middle cerebral artery occlusion (MCAO): signaling of the GDNF family of neurotrophic factors, and neurogenesis from endogenous progenitor cells. As determined by in situ hybridization for GDNF family ligand and receptor genes, MCAO caused widespread upregulation of both components of the functional GDNF receptor, c-Ret and GFRalpha1, indicating that GDNF may be a survival signal in stroke. LÄS MER