Sökning: "hormon"

Visar resultat 11 - 15 av 95 avhandlingar innehållade ordet hormon.

  1. 11. Secretory activity in isolated rat stomach ECL cells

    Författare :Erik Lindström; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocrinology; Calcium channels; Adrenaline; Pancreastatin; Prostaglandin E2; Galanin; Somatostatin; Histamine; Gastrin; VIP; PACAP; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi; Pharmacological sciences; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Sammanfattning : ECL cells are endocrine/paracrine cells located in the acid-producing part of the stomach. They are important regulators of gastric acid secretion in the stomach by virtue of their histamine synthesizing and secreting capacity. Histamine in turn stimulates parietal cells to secrete acid. LÄS MER

  3. 12. Upper gastrointestinal dysmotility - from endocrinological pathogenesis to symptoms

    Författare :Julia Borg; Enheten för kroniska inflammatoriska och degenerativa sjukdomar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oxytocin; gastroparesis; functional dyspepsia; upper gastrointestinal dysmotility; CCK; gastrin; vasopressin; esophageal dysmotility; satiety; diabetes mellitus; endocrine dysregulation; gastric emptying; gastric emptying scintigraphy; gastric emptying manometry; autonomic neuropathy;

    Sammanfattning : Gastrointestinal dysmotility is common, particularly in patients with diabetes mellitus. The aim of this thesis is to explore whether gastrointestinal dysmotility and endocrine secretion are interrelated, and how the symptoms manifest themselves in these patients. LÄS MER

  4. 13. Mechanisms by which variants in the TCF7L2 gene increase the risk of developing Type 2 diabetes

    Författare :Yuedan Zhou; diabetes och endokrinologi Genomik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TCF7L2; rs7903146; Type 2 diabetes; β cell function; β cell survival; insulin secretion; proinsulin synthesis; proinsulin-to-insulin conversion; insulin maturation; open chromain; exon skipping; p53; TP53INP1; ISL1; MAFA; NEUROD1; PDX1; NKX6.1; PCSK1; PCSK2; SLC30A8; GWAS.;

    Sammanfattning : Type 2 diabetes mellitus (T2DM) is a heterogeneous disease with a multifactorial aetiology comprising of genetic and environmental factors. The common variant most highly associated with T2DM known to date is a SNP rs7903146 in the TCF7L2 gene. However, the role TCF7L2 plays in the development of T2DM was unclear. LÄS MER

  5. 14. Neurohormonal Modulators in the Parathyroid Gland. Localization and regulation

    Författare :Lena Luts; Malmö Patologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Receptor; In situ hybridization; Immunocytochemistry; Nitric Oxide Synthase; Endothelin; Neuropeptides; Chromogranin; Parathyroid adenoma; Parathyroid gland; Parathyroid hormone; mRNA; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Sammanfattning : The occurrence and distribution of neurohormonal peptides, neuroendocrine markers and receptors in parathyroid nerve fibers and endocrine cells are described, using immunocytochemistry, in situ hybridization, image analysis and reverse transcriptase polymerase chain reaction. Immunocytochemical studies revealed that parathyroid glands of chicken, rat, guinea-pig, cat, dog and sheep contained adrenergic-, cholinergic-, and peptide-containing nerve fibers. LÄS MER

  7. 15. Ghrelin and CART. Two new islet peptides. Expression, regulation and function

    Författare :Nils Wierup; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endokrinologi; sekretion; diabetologi; Endocrinology; secreting systems; diabetology; histology; endocrinology; islets; CART; Ghrelin cells; insulin secretion; type-2 diabetes; Ghrelin;

    Sammanfattning : Until recently, the islets of Langerhans were thought to harbour four main cell types characterised with respect to principal hormone product. Here we show that the novel hormone ghrelin is expressed in a fifth islet cell type, the islet ghrelin cell, in humans and rodents. LÄS MER