Sökning: "hnRNPs"
Hittade 5 avhandlingar innehållade ordet hnRNPs.
1. Regulation of human papillomavirus 16 gene expression at the level of mRNA processing
Sammanfattning : .... LÄS MER
2. Molecular structure and intracellular location of five RNA : associated proteins in the salivary glands of the dipteran Chironomus tentans
Sammanfattning : The structure and intracellular flow of specific RNA-associated proteins have been characterized in the salivary gland cells in the dipteran Chironomus tentans. These cells contain four polytene chromosomes (I-IV), two of which harbour a nucleolus. LÄS MER
3. The role of hnRNP A1 and hnRNP C1/C2 in the regulation of the stress responsive genes Cyp2a5/2A6 and p53
Sammanfattning : The family of proteins known as heterogeneous nuclear ribonucleoproteins (hnRNPs) is large and diverse. Often, one and the same hnRNP will perform multiple cellular functions, leading to their description as “multifunctional proteins”. LÄS MER
4. Control of human papillomavirus type 1 late mRNA stability and translation by an AU-rich RNA element
Sammanfattning : Human Papillomaviruses (HPVs) infect the epithelial tissues in humans and infection with certain high-risk types is associated with cancer. The expressionof the HPV late capsid genes is dependent on cell differentiation. This may be one reason for the lack of HPV replication in vitro. LÄS MER
5. Somatostatin effects on the proteome of human prostate cancer cells
Sammanfattning : The transition of prostate cancer from androgen dependent to the therapy resistant androgen independent state, is a large and persistent problem in the clinical management of prostate cancer. The aim of this thesis was to study somatostatin effects on the proteome of prostate cancer cells, to identify differences in protein expression in androgen dependent and androgen independent prostate cancer cells, and to explore possibilities to enhance the somatostatin receptor expression through pre-treatment with sms, 5-aza and TSA (DNA methylation/HDAC inhibitors). LÄS MER