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Visar resultat 1 - 5 av 242 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Storage organelles that are distinct from the classical granules in human neutrophils

    Författare :Sara Pellmé; Göteborgs universitet; []
    Nyckelord :neutrophil; HL-60 cells; cytoplasts; granules; CXCL-8; ER; phagocytosis; HLA-I; subcellular fractionation; immunogold;

    Sammanfattning : The human neutrophil is a crucial participant in acute inflammation. Appropriate immune response is dependent on rapid direction of phagocytic cells through the tissue, towards the inflammatory focus. Such movement is governed by chemoattractants, e.g. LÄS MER

  3. 2. Compression analysis as a tool for technical characterization and classification of pharmaceutical powders

    Författare :Josefina Nordström; Göran Alderborn; Maria Strömme; Katharina Picker-Freyer; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; compaction; compression; granules; Kawakita; mechanical properties; particles; PAT; pharmaceutical powders; tablets; Pharmaceutics; Galenisk farmaci;

    Sammanfattning : There are today strong incentives for an increased understanding of material properties and manufacturing processes to facilitate the development of new technologies in the pharmaceutical industry. The purpose of this thesis was to suggest methods requiring a low sample amount for characterization of technical properties of powders. LÄS MER

  4. 3. Induction of Mast Cell Apoptosis via Granule Permeabilization : A Novel Approach to Target Mast Cells

    Författare :Aida Paivandy; Gunnar Pejler; Magda Babina; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mast cells; Granules; Apoptosis; Reactive oxygen species; ROS; Lysosomotropic agents; Mefloquine; Immunologi; Immunology; Biokemi; Biochemistry;

    Sammanfattning : Mast cells are densely granulated tissue-resident immune cells that play an important role in orchestrating inflammatory responses. Dysregulated increases in the numbers and activation status of mast cells can have deleterious consequences for the body in various inflammatory diseases. LÄS MER

  5. 4. Process analytical methods for monitoring of the film coating on pharmaceutical pellets and tablets using NIR spectrometry and image analysis

    Författare :Martin Andersson; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PLS; PCA; PAC; NIR; chemometrics; moving samples; information depth; release rate; image analysis; near infrared; process analytical chemistry; thickness; coating; film; tablets; Pellets; granules; Analytical chemistry; Analytisk kemi;

    Sammanfattning : Pharmaceutical tablets and pellets are often covered with a coating. There is a need for methods that enable monitoring of the growth of such films during processing. Such analyses can be performed using process analytical chemical methods based on near infrared (NIR) diffuse reflectance spectrometry. It provides with analyses that take only ca. LÄS MER

  7. 5. Interactions between surfactants and starch : from starch granules to amylose solutions

    Författare :Isabel Mira; Per Claesson; James N. Bemiller; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; food science and technology; polymer chemistry; Surface and colloid chemistry; Yt- och kolloidkemi;

    Sammanfattning : Starch is a mixture of two polysaccharides, amylose (AM) and amylopectin, which occurs naturally in the form of microscopic granules that are abundantly found in tubers, roots, cereal grains and fruits. In order to bring out their functional properties as thickeners and texture enhancers, starch granules are often disrupted by heating in excess water. LÄS MER