Sökning: "existing structure"

Visar resultat 1 - 5 av 811 avhandlingar innehållade orden existing structure.

  1. 1. From Sequence to Structure : Using predicted residue contacts to facilitate template-free protein structure prediction

    Författare :Mirco Michel; Arne Elofsson; Erik Lindahl; Johannes Söding; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein bioinformatics; protein structure prediction; contact prediction; machine learning; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

    Sammanfattning : Despite the fundamental role of experimental protein structure determination, computational methods are of essential importance to bridge the ever growing gap between available protein sequence and structure data. Common structure prediction methods rely on experimental data, which is not available for about half of the known protein families. LÄS MER

  3. 2. Footbridge Dynamics : Human-Structure Interaction

    Författare :Emma Zäll; Raid Karoumi; Mahir Ülker-Kaustell; Andreas Andersson; Peter Van den Broeck; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Dynamics; vibration; footbridge; pedestrian bridge; human-structure interaction; runner; running loads; simplified models; Dynamik; vibration; gångbro; människa-bro-interaktion; löpare; löparlaster; förenklade modeller; Civil and Architectural Engineering; Byggvetenskap;

    Sammanfattning : For aesthetic reasons and due to an increased demand for cost-effective and environmentally friendly civil engineering structures, there is a trend in designing light and slender structures. Consequently, many modern footbridges are susceptible to excessive vibrations caused by human-induced loads. LÄS MER

  4. 3. Development of rotation electron diffraction as a fully automated and accurate method for structure determination

    Författare :Bin Wang; Xiaodong Zou; Andy Stewart; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; electron crystallography; structure determination; structure refinement; metal-organic framework; guest molecules; software development; automation; hierarchical cluster analyses; high-throughput data processing; data merging; frame orientations; least-squares optimization; data processing; TEM goniometer; Inorganic Chemistry; oorganisk kemi;

    Sammanfattning : Over the past decade, electron diffraction methods have aroused more and more interest for micro-crystal structure determination. Compared to traditional X-ray diffraction, electron diffraction breaks the size limitation of the crystals studied, but at the same time it also suffers from much stronger dynamical effects. LÄS MER

  5. 4. Deep learning solutions to protein quaternary structure

    Författare :Gabriele Pozzati; Arne Elofsson; Emmanuel Levy; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein interactions; interface prediction; structure prediction; docking; deep learning; biokemi med inriktning mot bioinformatik; Biochemistry towards Bioinformatics;

    Sammanfattning : Interactions between proteins are directly involved in most biological processes and are essential for the correct functioning of every form of life. The nature of protein-protein interactions allows functional assemblies of hundreds of protein chains. LÄS MER

  7. 5. Structure Analysis of a Transient Protein Complex - NMR, X-ray crystallographic and Mass Spectrometric Studies of the Soluble Domains of the Proton-Pump Transhydrogenase from E. coli

    Författare :Tomas Johansson; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; nuclear magnetic resonance; proton-translocating transhydrogenase; structure; interactions; x-ray crystallography;

    Sammanfattning : Interactions between macromolecules in the cell are fundamental to life. However, many interactions are of a transient nature and are as such difficult to study at the atomic level using existing techniques. LÄS MER