Sökning: "early clinical studies"

Visar resultat 1 - 5 av 1413 avhandlingar innehållade orden early clinical studies.

  1. 1. On intestinal ischaemia after aortoiliac surgery : Epidemiological, clinical and experimental studies

    Författare :Martin Björck; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Ischaemia; intestines; colon; ischaemic colitis; aorta-abdominal; aortic aneurysm-abdominal; aortic rupture; atherosclerosis; postoperative complications; cohort studies; case-control studies; clinical protocols; experimental design; incidence; risk factors; diagnosis; treatment outcome; intra-mucosal pH; pHi; swine; splanchnic circulation; haemodynamics; dobutamine; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

    Sammanfattning : An important cause of death among patients undergoing surgery of the abdominal aorta is intestinal ischaemia. In the Swedish Vascular Registry 2930 aortoiliac operations were identified. The complication was studied in a combined cohort and case-control study, and multivariate analysis performed. The incidence of intestinal ischaemia was 2. LÄS MER

  3. 2. Metastatic spinal cord compression in prostate cancer : clinical and morphological studies

    Författare :Sead Crnalic; Richard Löfvenberg; Anders Widmark; Anders Bergh; Sten Nilsson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; bone metastasis; spinal cord compression; surgical treatment; survival prognosis; early diagnosis; androgen receptor; Orthopaedics; ortopedi; Pathology; patologi; Oncology; onkologi;

    Sammanfattning : Background: Bone metastases occur in most patients with advanced hormone-refractory prostate cancer causing pain, pathologic fractures, and spinal cord compression. Few studies specifically address surgical treatment of metastatic spinal cord compression (MSCC) in prostate cancer. LÄS MER

  4. 3. Hyperglycemia and Focal Brain Ischemia : Clinical and Experimental Studies

    Författare :Nasim Farrokhnia; Andreas Terént; Fredrik Lennmyr; Elisabeth Björk; Henrik Hagberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Internal medicine; cerebrovascular disorders; diabetes mellitus; hyperglycemia; infarction; middle cerebral artery; ischemia; mitogen-activated protein kinases; mortality; rats; reactive oxygen species; reperfusion; signal transduction; therapeutics; Invärtesmedicin; Internal medicine; Invärtesmedicin;

    Sammanfattning : Diabetes is a major risk factor for ischemic stroke and is associated with increased mortality. Additionally, hyperglycemia, a common complication in acute stroke, is associated with poor outcome. LÄS MER

  5. 4. Vitamin A and Osteoporosis : Experimental and Clinical Studies

    Författare :Sara Johansson; Håkan Melhus; Andreas Kindmark; Monica Lind; Göran Toss; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Internal medicine; vitamin A; bone; osteoporosis; Invärtesmedicin; Internal medicine; Invärtesmedicin;

    Sammanfattning : Vitamin A in high doses is severely toxic to the rat skeleton, and the active metabolite retinoic acid (RA) can induce bone resorption in vitro. An excessive dietary intake of vitamin A has been associated with reduced bone mineral density and an increased risk of hip fracture. LÄS MER

  7. 5. Postoperative pain, inflammation and functional recovery after total hip arthroplasty : Prospective, randomized, clinical studies

    Författare :Jan Kuchalik; Anil Gupta; Anders Lundin; Mats Enlund; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Total hip arthroplasty; local infiltration analgesia; intrathecal morphine; femoral nerve block; postoperative pain; spinal anesthesia;

    Sammanfattning : Total hip arthroplasty (THA) is performed in patients with osteoarthritis of the hip joint. Pain following THA is often moderate but no gold stand-ard exists for pain management. Good postoperative pain management may lead to a better quality of life and hip function. LÄS MER