Sökning: "droplet fission"

Hittade 2 avhandlingar innehållade orden droplet fission.

1. 1. Analysis of noncovalent and covalent protein-ligand complexes by electrospray ionisation mass spectrometry

   Författare :Gustav Sundqvist; Harry Brumer; Per Andrén; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; noncovalent complex; droplet fission; nano-electrospray ionisation; mass spectrometry; Analytical chemistry; Analytisk kemi;

   Sammanfattning : In this thesis, the application of electrospray ionisation mass spectrometry (ESI-MS) to the analysis of intact proteins is demonstrated. In papers I and II, the use of ESI-MS for the analysis of noncovalent protein-ligand complexes were discussed. LÄS MER

3. 2. Astrocytes in Alzheimer’s disease : Exploring the impact of amyloid-β pathology on neurotoxicity, metabolism and inflammation

   Författare :Chiara Beretta; Anna Erlandsson; Dag Sehlin; Christian Tackenberg; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; astrocytes; amyloid-beta; extracellular vesicles; mitochondria; lipid droplets; lipid metabolism; inflammation; Molekylär medicin; Molecular Medicine;

   Sammanfattning : Astrocytes play a central role in brain homeostasis, but are also tightly connected to the pathogenesis of Alzheimer’s disease (AD). Yet, their exact role in amyloid-beta (Aβ) pathology and chronic neuroinflammation is unclear. The aim of this thesis was to elucidate the impact of astrocytes in AD progression. LÄS MER