Sökning: "dioxin-like compounds"

Visar resultat 1 - 5 av 15 avhandlingar innehållade orden dioxin-like compounds.

  1. 1. Bioassay analysis of dioxin-like compounds : response interactions and environmental transformation of Ah receptor agonists

    Författare :Helena Olsman; Magnus Engwall; John P. Giesy; Örebro universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; bioassay; dioxin-like; Ah receptor; Biology; Biologi; Biology; Biologi;

    Sammanfattning : Dioxin-like compounds mediate their toxicity by binding to the aryl hydrocarbon receptor (AhR) and through this receptor a cascade of biochemical and toxic events are triggered. Mechanism-specific dioxin bioassays utilise the AhR coupled induction of endogenous CYP1A proteins or reporter gene systems for detection of dioxin-like compounds and other AhR ligands. LÄS MER

  2. 2. Thermal formation and chlorination of dioxins and dioxin-like compounds

    Författare :Stina Jansson; Stellan Marklund; Mats Tysklind; Jochen F. Müller; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; dioxin; dioxin-like compounds; isomer distribution pattern; homologue profile; injection; O2PLS; PCDD; PCDF; PCN; PCBz; PCPh; MSW combustion; formation; chlorination; flue gas; quench profiles; Environmental chemistry; Miljökemi;

    Sammanfattning : This thesis contributes to an increased understanding of the formation of dioxins and dioxin-like compounds in combustion processes. Although emissions to air from waste incineration facilities have been greatly reduced by the use of efficient air pollution control measures, the resulting residues (ashes and filters) are highly toxic and are classified as hazardous waste. LÄS MER

  3. 3. Computational methods for analyzing dioxin-like compounds and identifying potential aryl hydrocarbon receptor ligands : multivariate studies based on human and rodent in vitro data

    Författare :Malin Larsson; Patrik Andersson; Anna Linusson; Mats Tysklind; Scott Boyer; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; dioxin-like compounds; multivariate analysis; toxic equivalency factor; quantitative structure-activity relationship; descriptors; virtual screening; in vitro; species variation; aryl hydrocarbon receptor;

    Sammanfattning : Polychlorinated dibenzo-p-dioxins/dibenzofurans (PCDD/Fs) and polychlorinated biphenyls (PCBs) are omnipresent and persistent environmental pollutants. In particular, 29 congeners are of special concern, and these are usually referred to as dioxin-like compounds (DLCs). LÄS MER

  4. 4. Properties and analysis of dioxin-like compounds in marine samples from Sweden

    Författare :Kjell Lundgren; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Environmental chemistry; planar dioxin-like compound; polychlorinated dibenzofuran; polychlorinated biphenyl; polychlorinated naphthalene; alkylated polychlorinated dibenzofuran; high-performance liquid chromatography; PX-21 carbon column; biomagnification factor; biota to sediment accumulation factor; fluxes; relative retention time; mass spectrometry; relative response factor; ultra-violet spectroscopy; Miljökemi; Environmental chemistry; Miljökemi; analytisk kemi; Analytical Chemistry;

    Sammanfattning : Polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs), and dioxin-like polychlorinated biphenyls (PCBs) have been assigned toxic equivalency factors (TEFs). These compounds are today routinely analysed with sophisticated analytical techniques. LÄS MER

  5. 5. PLE with integrated clean up followed by alternative detection steps for cost-effective analysis of dixons and dioxin-like compounds

    Författare :Erik Spinnel; Peter Haglund; Patrik Andersson; Tuulia Hyötyläinen; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Pressurized liquid extraction PLE ; PLE-C; modular PLE; ELISA; dioxin; dioxin-like compounds; GCxGC; analytical methods; Environmental chemistry; Miljökemi;

    Sammanfattning : Polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) are two structurally related groups of chemicals, generally referred to as `dioxins´. These are of great concern due to their high toxicity and global spread. LÄS MER