Sökning: "homologue profile"

Visar resultat 1 - 5 av 9 avhandlingar innehållade orden homologue profile.

  1. 1. Thermal formation and chlorination of dioxins and dioxin-like compounds

    Författare :Stina Jansson; Stellan Marklund; Mats Tysklind; Jochen F. Müller; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; dioxin; dioxin-like compounds; isomer distribution pattern; homologue profile; injection; O2PLS; PCDD; PCDF; PCN; PCBz; PCPh; MSW combustion; formation; chlorination; flue gas; quench profiles; Environmental chemistry; Miljökemi;

    Sammanfattning : This thesis contributes to an increased understanding of the formation of dioxins and dioxin-like compounds in combustion processes. Although emissions to air from waste incineration facilities have been greatly reduced by the use of efficient air pollution control measures, the resulting residues (ashes and filters) are highly toxic and are classified as hazardous waste. LÄS MER

  3. 2. Sources of dioxins and other POPs to the marine environment : Identification and apportionment using pattern analysis and receptor modeling

    Författare :Kristina Sundqvist; Karin Wiberg; Mats Tysklind; Paul Geladi; Miriam Diamond; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; air-water gas exchange; chiral; congener pattern; enantiomer; enantiomeric fraction; fugacity; HCH; hexachlorocyclohexane; homologue profile; indicator congener; isomer pattern; pattern analysis; PCA; PCB; PCDD F; PMF; polychlorinated dibenzofuran; polychlorinated dibenzo-p-dioxin; polychlorinated biphenyl; positive matrix factorization; principal component analysis; receptor modeling; source apportioning; source; source tracing; Environmental chemistry; Miljökemi; Persistent organic compounds; Persistenta organiska föreningar;

    Sammanfattning : In the studies underlying this thesis, various source tracing techniques were applied to environmental samples from the Baltic region. Comprehensive sampling and analysis of polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) in surface sediments in Swedish coastal and offshore areas resulted in a unique data set for this region. LÄS MER

  4. 3. From protein sequence to structural instability and disease

    Författare :Lixiao Wang; Uwe Sauer; Sven Hovmöller; Umeå universitet; []
    Nyckelord :protein domain; remote homologue; intrinsically disorder unstructured proteins; protein function; point mutation; protein family protein stability; HMMs; CRFs; SVMs;

    Sammanfattning : A great challenge in bioinformatics is to accurately predict protein structure and function from its amino acid sequence, including annotation of protein domains, identification of protein disordered regions and detecting protein stability changes resulting from amino acid mutations. The combination of bioinformatics, genomics and proteomics becomes essential for the investigation of biological, cellular and molecular aspects of disease, and therefore can greatly contribute to the understanding of protein structures and facilitating drug discovery. LÄS MER

  5. 4. Functional and Molecular Characterization of Centrally Expressed Genes Associated with Obesity

    Författare :Anders Eriksson; Helgi Schiöth; Christian Broberger; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroscience; Neurovetenskap;

    Sammanfattning : Obesity is a complex disorder that has reached epidemic proportions in the Western world, currently affection more than two billion people. The evidence for the genetic influence on obesity has been estimated to be as high as 70% based on twin studies. LÄS MER

  7. 5. Ribosome display for selection and evolution of affibody molecules

    Författare :Sebastian Grimm; Per-Åke Nygren; Mike Taussig; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; affibody; ribosome display; phage display; combinatorial protein engineering; library; murine IgG1; SATB1; Ras; Raf; Genetic engineering including functional genomics; Genteknik inkl. funktionsgenomik; SRA - Molecular Bioscience; SRA - Molekylär biovetenskap;

    Sammanfattning : Affinity proteins are invaluable tools in biotechnological and medical applications. This thesis is about combinatorial protein engineering principles for the generation of novel affinity proteins to purify mouse immunoglobulin, detect a potential cancer marker protein or inhibit a cell proliferation pathway. LÄS MER