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Visar resultat 1 - 5 av 72 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Oxidation of 1,2-Diols Using Alcohol Dehydrogenases : From Kinetic Characterization to Directed Evolution

   Författare :Cecilia Blikstad; Mikael Widersten; Stefan Lutz; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; enzyme kinetics; alcohol dehydrogenase; directed evolution; enzyme engineering; diol; α-hydroxy aldehyde; Biokemi; Biochemistry;

   Sammanfattning : The use of enzymes as catalysts for chemical transformations has emerged as a “greener” alternative to traditional organic synthesis. An issue to solve though, is that enzymes are designed by nature to catalyze reactions in a living cell and therefore, in many cases, do not meet the requirements of a suitable biocatalyst. LÄS MER

3. 2. Characterization of two novel fatty acid dioxygenases : Linoleate diol synthase and manganese lipoxygenase

   Författare :Chao Su; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Dioxygenase; hemeprotein; lipoxygenase; metalloenzyme; oxylipin; fatty acid; manganese-protein; Gaeumannomyces graminis; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; galenisk farmaci; Pharmaceutics;

   Sammanfattning : Two classes of fatty acid dioxygenases, PGH synthases (hemeproteins) and lipoxygenases (non-heme iron proteins), are of eminent pharmacological importance. This thesis describes a PGH synthase-related dioxygenase designated linoleate diol synthase (LDS) and the first native occurring manganese-containing lipoxygenase. LÄS MER

4. 3. Enzymatic synthesis of monoglycerides by glycerolysis of rapeseed oil

   Författare :Inger Elfman Börjesson; Chalmers tekniska högskola; []
   Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; monoglycerides; water activity; HPLC; immobilised enzyme; rapeseed oil; evaporative light-scattering detector; glycerolysis; response surface methodology; lipase; diol column;

   Sammanfattning : .... LÄS MER

5. 4. FACING THE CHALLENGE OF SKIN PENETRATION - A STUDY ON LIPIDIC LIQUID CRYSTALLINE PHASES FOR DERMAL DRUG DELIVERY

   Författare :Hanne Evenbratt; Chalmers tekniska högskola; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; 5-diol; liquid crystalline phases; N-Methyl-2-pyrrolidone; pentane-1; glyceryl monooleat; propylene glycol; dermal drug delivery; glyceryl monooleyl ether; cubic phase; reversed hexagonal phase;

   Sammanfattning : The skin is a barrier which protects us against daily attacks of foreign substances. From a pharmaceutical perspective it is also an interesting delivery route with its large surface and possibility to reach the blood stream circumventing first passage metabolism. With the varied size, structure etc. LÄS MER

7. 5. Conformation and dynamics of DNA : effects of covalent binding of benzo(a)pyrene diol epoxide

   Författare :Per-Olof Lycksell; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : .... LÄS MER