Sökning: "anti-viral treatment"

Visar resultat 1 - 5 av 16 avhandlingar innehållade orden anti-viral treatment.

  1. 1. On causes and regulation of anti-viral defence in asthma and COPD

    Detta är en avhandling från Lund University, Faculty of Medicine

    Författare :Mandy Menzel; Lunds universitet.; Lund University.; [2018]
    Nyckelord :asthma; chronic obstructive pulmonary disease; rhinovirus; exacerbation; airway epithelial cell; ; pattern recognition receptors; interferon; allergen; azithromycin; inflammasome; epithelial-derived cytokines; oxidative stress; asthma; chronic obstructive pulmonary disease; rhinovirus; exacerbation; airway epithelial cell; pattern recognition receptors; interferon; allergen; azithromycin; inflammasome; epithelial-derived cytokines; oxidative stress;

    Sammanfattning : Rhinovirus infection is a main trigger of asthma and COPD exacerbations. dsRNA, a viral replication intermediate, is sensed by pattern recognition receptors in the airway epithelium leading to down-stream induction of anti-viral interferons. LÄS MER

  2. 2. Studies of specific immunity against viral infections in patients after stem cell transplantation

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Medicine at Huddinge University Hospital

    Författare :Gayane Avetisyan; Karolinska Institutet.; Karolinska Institutet.; [2007]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Stem cell transplantation; cytomegalovirus; influenza; cellular and humoral immunity; immunological monitoring; anti-viral treatment; vaccination;

    Sammanfattning : Recipients of allogeneic hematopoietic stem cell transplantation (allo-HSCT) experience a prolonged period of immune deficiency, resulting in significant morbidity and mortality from the infections. Viruses such as cytomegalovirus (CMV) and influenza virus are frequent causes of infectious complications following allo-HSCT. LÄS MER

  3. 3. Hepatitis C in chronic kidney disease and kidney transplantation : With special reference to epidemiology and treatment

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Medicine at Huddinge University Hospital

    Författare :Annette Bruchfeld; Karolinska Institutet.; Karolinska Institutet.; [2003]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hepatitis C; kidney transplantation; patient and graft survival; renal replacement therapy; dialysis; renal insufficiency; interferon-alpha; ribavirin; plasma concentration; anaemia; population pharmacokinetics; renal function.;

    Sammanfattning : Hepatitis C (HCV) is a clinical problem in infected kidney transplant patients but is also a cause of renal disease and vasculitis. Standard therapy for HCV is a combination of interferon and ribavirin. LÄS MER

  4. 4. Interaction Characteristics of Viral Protease Targets and Inhibitors Perspectives for drug discovery and development of model systems

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Cynthia F Shuman; Uppsala universitet.; [2003]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; viral proteases; biomolecular interactions; kinetics; thermodynamics; biosensors; drug discovery; Biokemi; NATURAL SCIENCES Chemistry Biochemistry; NATURVETENSKAP Kemi Biokemi; Biokemi; Biochemistry;

    Sammanfattning : Viral proteases are important targets for anti-viral drugs. Discovery of protease inhibitors as anti-viral drugs is aided by an understanding of the interactions between viral protease and inhibitors. This thesis addresses the characterization of protease-inhibitor interactions for application to drug discovery and model system development. LÄS MER

  5. 5. The clinical perspective on malignancies in renal transplanted patients

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Vivan Hellström; Uppsala universitet.; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; renal transplantation; malignant tumours;

    Sammanfattning : Post-transplant malignancies cause significant morbidity and mortality. In this thesis we investigated malignancies in renal transplanted patients from a clinical viewpoint. The use of regional tumour registries considerably improved identification of pre- and post-transplant malignancies, which are generally underreported in transplant registries. LÄS MER