Sökning: "malignant tumours"

Visar resultat 1 - 5 av 159 avhandlingar innehållade orden malignant tumours.

  1. 1. Midgut Carcinoid Tumours : New Diagnostic Procedures and Treatment

    Författare :Staffan Welin; Eva T. Janson; Barbro Eriksson; Larry Kvols; Uppsala universitet; []
    Nyckelord :Medicine; Midgut carcinoid tumour; Chromogranin A; Carcinoid heart disease; Survival; Octreotide pamoate; Tyrosine kinase receptors; Platelet derived growth factor receptor; Epidermal growth factor receptor; Medicin;

    Sammanfattning : Midgut carcinoid tumours are rare with an incidence of 0.5-2.1/100 000. The primary tumour is usually small and grows slowly but has almost always set metastases at diagnosis. LÄS MER

  3. 2. Patient and health care delays in malignant melanoma

    Författare :Senada Hajdarevic; Marcus Schmitt-Egenolf; Carol Tishelman; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Care seeking; delay; diagnosis; decision making; gender; malignant melanoma; nursing; organization; pathways; severity; Allvarlighetsgrad; att söka vård; beslutsfattande; diagnos; fördröjning; genus; malignt melanom; omvårdnad; organisation; remissvägar; omvårdnadsforskning med medicinsk inriktning; Caring Sciences;

    Sammanfattning : Background: Unlike other cancers, malignant melanoma (MM) is generally visible and can be easily and effectively cured if treated in time. Optimal cure of MM requires early detection, diagnosis, and treatment, which improves prognosis. LÄS MER

  4. 3. Affibody Molecules for HER3-targeted Theranostics of Malignant Tumours

    Författare :Maria Rosestedt; Anna Orlova; Vladimir Tolmachev; Olof Eriksson; Sten Nilsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; affibody molecules; theranostics; HER3; molecular imaging;

    Sammanfattning : The HER3 receptor plays a strong role in disease progression and resistance to therapies in several cancer types. Due to its endogenous expression and low overexpression in malignant tumours, it is a particularly challenging target. LÄS MER

  5. 4. Mechanisms and Consequences of Chromosomal Instability in Malignant tumours

    Författare :Ylva Stewénius; Avdelningen för klinisk genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; structural rearrangement; Ewing family tumour; Chromosomal instability; nephroblastoma; Wilms tumour; chromosomal aberration; anaphase bridge; subtelomeric FISH; breakage-fusion-bridge cycle;

    Sammanfattning : In this thesis, telomere deficiency with subsequent anaphase bridging was found to be associated with chromosomal instability in established colorectal cancer cell lines and in Wilms tumour. In colorectal cancer cell lines, anaphase bridging was observed to generate both numerical and structural chromosomal aberrations and was also associated with the presence of multipolar mitoses. LÄS MER

  7. 5. Differential RNA expression in benign and malignant adrenocortical tumours

    Författare :David Velázquez-Fernández; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Adrenocortical; microarray; mRNA; cancer; tumors; cDNA; expression profiles; aldosterone; cortisol; endocrine; adenomas; carcinomas; IGF2; ALDH1A1.;

    Sammanfattning : Adrenocortical cancer is a rare but very aggressive endocrine tumor, with a yearly incidence of 0.5 to 2 cases per million inhabitants, accounting for 0.2% of all cancer related deaths. LÄS MER