Sökning: "adipose derived stem cells"

Visar resultat 1 - 5 av 20 avhandlingar innehållade orden adipose derived stem cells.

1. 1. Keratinocytes and Adipose-derived mesenchymal stem cells : The heir and the spare to regenerative cellular therapies for difficult-to-heal skin wounds

   Författare :Hady Shahin; Ahmed Taher Elserafy; Moustafa Elmasry; Folke Sjöberg; Ingrid Steinvall; Daniel Nowinski; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Keratinocytes; ATMP; Bio-production; Adipose-derived mesenchymal stem cells; Wound healing;

   Sammanfattning : Cell-based therapy is considered as Advanced Therapy Medicinal Product, (ATMP), which had increasingly stricter regulations in the last decade. The cells must be produced according to the ‘Guidelines on Good Manufacturing Practice (GMP) specific to Advanced Therapy Medicinal Products’, adopted by the European Medicines Agency (EMA). LÄS MER

3. 2. Optimizing stem cells for reconstructive surgery

   Författare :Anne Therese Lauvrud; Paul J. Kingham; Rebecca Wiberg; Peyman Kelk; Maria Brohlin; Susanna Kauhanen; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adipose tissue-derived stem cells; liposuction; oncological safety; xenofree growth medium; Human Anatomy; anatomi;

   Sammanfattning : Fat grafting has become an established method in plastic surgery for treating soft tissue defects. The results for survival of the fat being transplanted is unpredictable and supplementation of the graft with the Stromal Vascular Fraction (SVF) or cultures Adipose tissue-derived stem cells (ASCs) can enhance graft viability. LÄS MER

4. 3. The use of adipose derived stem cells in spinal cord and peripheral nerve repair

   Författare :Mallappa K Kolar; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; spinal cord injury; peripheral nerve injury; adipose derived stem cells; regeneration; neurotrophic factor; angiogenic factor;

   Sammanfattning : Clinically, injuries affecting the spinal cord or peripheral nerves can leave those affected with severe disability and, at present, there are limited options for treatment. Peripheral nerve injury with a significant gap between the proximal and distal stumps is currently treated with autologous nerve grafting but this is limited by availability of donor nerve and has associated morbidities. LÄS MER

5. 4. Stem cells for nerve repair and prevention of muscle atrophy

   Författare :Dominique Schaakxs; Paul Kingham; Mikael Wiberg; Daniel Kalbermatten; Christine Radtke; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipose stem cells; biomaterial; muscle; nerve injury; neuromuscular junction; regeneration; cell research; cellforskning; Medical Cell Biology; medicinsk cellbiologi;

   Sammanfattning :   Peripheral nerve injury (PNI) is common and despite modern microsurgical techniques of repair, functional restoration is always incomplete. This results in impaired sensation and reduced motor function alongside pain and cold intolerance. LÄS MER

7. 5. Adipose Tissue Heterogeneity - Development and Application of Nonlinear Microscopy Methods

   Författare :Alexandra Paul; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; least squares decomposition; stem cells; multivariate spectral analysis; obesity; adipose tissue; adipogenesis; broadband coherent anti-Stokes Raman scattering; extracellular matrix;

   Sammanfattning : Although the negative health impacts of obesity have been well documented, the number of overweight or obese patients has and is predicted to continue rising. One of the causal factors of obesity is a constant positive energy balance mainly from excessively high caloric intake from food compared with limited physical activity (caloric expenditure). LÄS MER