Sökning: "USF"

Visar resultat 1 - 5 av 11 avhandlingar innehållade ordet USF.

  1. 1. Regulation of HIV-1 provirus transcription

    Författare :Mojgan H Naghavi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Key words- HIV-1; LTR; transcription; subtypes; phylogenetic analysis; NFkappaB; USF; MCEF; HMG-1 DSP1; Dorsal.;

    Sammanfattning : Transcription of the HIV-genome is regulated by the interaction of viral long terminal repeat (LTR) cis-acting sequences with a complex of viral regulatory proteins and cellular transcription factors. The complex interplay between the cellular-, and/or viral proteins and LTR of different subtypes may play a role in the control of HIV-1 latency versus activation. LÄS MER

  3. 2. First-principles description of planarfaults in metals and alloys

    Författare :Wei Li; Levente Vitos; Ujfalassy Habil Balazs; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : Phase interface and stacking fault are two common planar defects in metallic materials. In the present thesis, the interfacial energy and the generalized stacking fault energy of random alloys are investigated using density functional theory formulated within the exact muffin-tin orbitals (EMTO) method in combination with the coherent-potential approximation (CPA). LÄS MER

  4. 3. Purification of general RNA polymerase II transcription factors from mouse for studies of proliferation-specific transcription

    Författare :Irina Kotova; Lars-Gunnar Larsson; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular genetics; Genetik; Genetics; Genetik;

    Sammanfattning : Accurate initiation of transcription by RNA polymerase II depends on general transcription factors (GTFs), which include the TATA-binding protein (TBP) and the transcription factors (TF) IIB, IIF, IIE and IIH. In order to reconstitute mouse transcription in vitro, we cloned the genes encoding mouse TFIIB, and both subunits of TFIIE and TFIIF from a mouse cDNA library. LÄS MER

  5. 4. The immunoglobulin heavy chain 3ʼ enhancer : coupling of basic-Helix-Loop-Helix proteins to the regulation of enhancer function

    Författare :Velmurugesan Arulampalam; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : During B lymphocyte development, the transcriptional activity of the IgH locus is subject to spatial and temporal changes. One cis-control element, the IgH 3' enhancer, has been implicated in regulating functional events in late B cell development. LÄS MER

  7. 5. Inducible and constitutive modes of gene regulation by the dioxin receptor and Arnt

    Författare :Camilla Antonsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Heterodimeric complexes between the basic helix-loop-helix (bHLH)/PAS (Per-Arnt-Sim) transcription factors, dioxin receptor and Arnt, are involved in mediating cellular responses to 2,3,7,8-tetrachlorodibenzo-p-dioxin (dioxin). The unliganded dioxin receptor is found in the cytoplasm complexed with the 90-kDa heat shock protein hsp90, in a latent inactive (non-DNA binding) configuration. LÄS MER