Sökning: "Irina Kotova"

Hittade 1 avhandling innehållade orden Irina Kotova.

1. 1. Purification of general RNA polymerase II transcription factors from mouse for studies of proliferation-specific transcription

   Författare :Irina Kotova; Lars-Gunnar Larsson; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular genetics; Genetik; Genetics; Genetik;

   Sammanfattning : Accurate initiation of transcription by RNA polymerase II depends on general transcription factors (GTFs), which include the TATA-binding protein (TBP) and the transcription factors (TF) IIB, IIF, IIE and IIH. In order to reconstitute mouse transcription in vitro, we cloned the genes encoding mouse TFIIB, and both subunits of TFIIE and TFIIF from a mouse cDNA library. LÄS MER