Sökning: "RAMPs"

Visar resultat 1 - 5 av 16 avhandlingar innehållade ordet RAMPs.

  1. 1. The calcitonin gene family of peptides : receptor expression and effects on bone cells

    Författare :Susanne Granholm; Ulf Lerner; Pernilla Lundberg; Göran Andersson; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; CT family of peptides; osteoclast differentiation; bone resorption; CTR; CRLR; RAMPs; Cell biology; Cellbiologi;

    Sammanfattning : The calcitonin gene family of peptides consists of calcitonin (CT), two calcitonin gene related peptides (α-CGRP, β-CGRP), adrenomedullin (ADM), amylin (AMY), three calcitonin receptor activating peptides (CRSP1-3) and intermedin/adrenomedullin2 (IMD). These peptides bind to one of two G protein -coupled receptors, the calcitonin receptor (CTR) or the calcitonin receptor-like receptor (CRLR). LÄS MER

  3. 2. Optimisation of horizontal alignments for railways - Procedures involving evaluation of dynamic vehicle response

    Författare :Björn Kufver; KTH; []
    Nyckelord :Railway; track geometry; alignment; cant; climbing ratios; clothoids; guiding forces; passenger comfort; Pct; superelevation ramps; simulation; track shift forces; track vehicle interaction; transition curves; vehicle dynamics; wheel rail forces;

    Sammanfattning : This doctoral thesis summarises and deepens eightpublications on a project concerning railway alignments.The thesis presents an approach to definingequally costlyalignment alternatives. LÄS MER

  4. 3. Ramp Josephson junctions based on NdBa2Cu3O7-δ electrodes and PrBa2Cu3O7-δ barriers

    Författare :Mikael Sjöstrand; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; PBCO; high temperature; superconducting device; ramp Josephson junction; NBCO; pulsed laser deposition; thin film;

    Sammanfattning : We report on smooth high quality c-axis orientedNdBa2Cu3O7-δ (NBCO) superconducting thin filmsgrown on (001) SrTiO3 substrates using pulsed laser deposition.The transition temperature of these NBCO films was around 89.5 Kand the root-mean-square (RMS) surface roughness was 0.75 nm for150 nm thick films. LÄS MER

  5. 4. On the application and validation of multiplexed affinity assays

    Författare :Tea Dodig-Crnković; Jochen M. Schwenk; Mun-Gwan Hong; Peter Nilsson; Norman Leigh Anderson; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Affinity proteomics; Antibody; Autoantibody; Multiplexed assays; Protein microarray; Plasma proteins; Suspension bead array; Bioteknologi; Biotechnology;

    Sammanfattning : Proteins are essential macromolecules that carry out complex functions in human cells, tissues, and organs. They regulate a diverse set of biological processes and protect against pathogens. However, dysregulation or malformation of proteins can cause disease. LÄS MER

  7. 5. Coordination and Analysis of Connected and Autonomous Vehicles in Freeway On-Ramp Merging Areas

    Författare :Jie Zhu; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Operational efficiency; Safety impacts; Freeway on-ramp merging; Microscopic traffic simulation; Connected and autonomous vehicles; Coordinative merging strategy;

    Sammanfattning : Freeway on-ramps are typical bottlenecks in the freeway network, where the merging maneuvers of ramp vehicles impose frequent disturbances on the traffic flow and cause negative impacts on traffic safety and efficiency. The emerging Connected and Autonomous Vehicles (CAVs) hold the potential for regulating the behaviors of each individual vehicle and are expected to substantially improve the traffic operation at freeway on-ramps. LÄS MER